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B2 - Hemostasia. > Clopidogrel > Flashcards

Clopidogrel Flashcards

1
Q

Mecanismo de acción

A

Inhibición del receptor P2Y12 de ADP en plaquetas; inhibe por lo tanto la síntesis de GPIIa y la agregación plaquetaria

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2
Q

Indicaciones

A

Infarto al miocardio, infarto cerebral, síndrome coronario agudo.

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3
Q

Reacciones adversas

A

Epixtasis, hemorragias, dispepsia, equimosis, erupción cutánea

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4
Q

Metabolismo

A

CYP2C19 (mayor), CYP3A4 (menor)

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5
Q

Consideraciones especiales

A

Inhibe el metabolismo de antiinflamatorios no esteroides, fenitoína, fluvastatina

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B2 - Hemostasia. (6 decks)

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