Clinical trial design to reduce bias Flashcards
1
Q
List the sources of bias in clinical trials
A
Selection bias Performance bias Attrition bias Observer bias Detection bias Reporting bias
2
Q
What is selection bias?
A
Systematic differences in selecting groups for comparison
differences between baseline characteristics of the groups that are compared
3
Q
What is performance bias?
A
Systematic differences in the treatment/care of groups, other than the interventions of interest.
4
Q
What is detection bias?
A
Systematic differences between groups in how outcomes are determines
5
Q
What is attrition bias?
A
Systematic differences between groups in withdrawal from a study.
6
Q
What is observer bias?
A
Failure to measure or classify the exposure of outcomes appropriately.
