Clinical Terms Flashcards
FEV
Forced Expiratory Volume (FEV) measures how much air a person can exhale during a forced breath. The amount of air exhaled may be measured during the first (FEV1), second (FEV2), and/or third seconds (FEV3) of the forced breath.
FVC
Forced vital capacity (FVC) is the TOTAL amount of air exhaled during the FEV test
Spirometry
Test measures the amount of air a person’s lungs can move in and out and at what rate. The person places her mouth on the mouthpiece that is attached to a recording device (spirometer). The person breathes in (inhales) as deeply as possible. The person then blows out (exhales) as hard, fast, and completely as possible.
FeNO
Fractional Exhaled nitric oxide (FeNO): 1) Measures airway inflammation and how well inhaled steroids suppress inflammation, 2) Determines steroid responsiveness and optimizes the dose of inhaled corticosteroids, 3) Assists with diagnosis of asthma and patients with Th2/Type 2 Allergic/Eosinophilic Inflammation, 4) Blow slowly and steadily, not hard and fast
Nitric Oxide
Nitric oxide is a gas produced by cells involved in the inflammation associated with allergic or eosinophilic asthma
DLCO
Diffusing Capacity of Lung for Carbon Monoxide (DLCO) measures the ease of transfer for CO molecules from alveolar gas to the hemoglobin of the red blood cells in the pulmonary circulation. Evaluates the presence of parenchymal lung disease when spirometry or lung volume tests suggest a reduced vital capacity, RV, and/or TLC.
TQT
Thorough QT (TQT) study evaluates QT interval prolongation in healthy volunteers using a double-blind, randomized, placebo and active controlled study. It is calculated as the time from the start of the Q wave to the end of the T wave, and approximates to the time taken from when the cardiac ventricles start to contract to when they finish relaxing. An abnormally long or short QT interval is associated with an increased risk of developing abnormal heart rhythms and sudden cardiac death
