Clinical Study Day 1, Patient C

Question 1

What are the signs of sepsis infection?

Answer 1

Mottled, bluish or pale skin. 
Very lethargic or difficult to wake.
Abnormally cold to the touch. 
Fast breathing. 
Rash that does not fade when you press it. 
Fits/Convulsions. 
Fast heartbeat.

Question 2

What are the risk factors for sepsis?

Answer 2

The very young or the very old.

People who have an impaired immune system.

Recent surgery (last 6 weeks).

Any breach of skin integrity (cuts, burns, blisters or skin infections).

IV drugs users.

People with indwelling lines or catheters.

Question 3

How are people with suspected sepsis managed outside the acute hospital settings?

Answer 3

Refer all people with suspected sepsis, who do have any high or moderate to high risk critieria to acute hospital settings.

Provide people with suspected sepsis, who do not have any high or moderate to high risk criteria information about symptoms to monitor and how to access medical care if they are concerned.

Question 4

Adults, children and young people aged 12 years and over with suspected sepsis who meet 1 or more high risk criteria should recieve what?

Answer 4

A broad-spectrum antimicrobial at the maximum recommended dose without delay (within 1 hours of identifying that they meet any high risk criteria in an acute hospital setting.

Question 5

If in a patient with sepsis, meningococcal disease is specifically suspected (fever and purpuric rash) appropriate doses of which antibiotic should be given in community settings and which antibiotic in hospital settings?

Answer 5

Parenteral benzyl penicillin in community.

Intravenous ceftriaxone in hospital settings.

Question 6

For people aged up to 17 years with suspected community acquired sepsis of any cause give what antibiotic at what dosing regimen?

Answer 6

Give ceftriaxone 80mg/kg once a day with a maximum dose of 4g daily at any age.

Question 7

What are the red flags for use of sulfasalzine?

Answer 7

Sore throat, any other signs of infection etc.