Clinical Significance

Question 1

What is the causative agent of food poisoning?

Answer 1

C. perfringens

Question 2

What is also known as gas gangrene and is most commonly caused by C. perfringens?

Answer 2

Myonecrosis

Question 3

What toxins are produced by Myonecrosis?

Answer 3

Alpha toxin (Necrosis)
May require amputation

Question 4

What are the causative agents of Bacteremia?

Answer 4

C. perfringens (Blood cultures Isolate)
C. septicum (GI malignancy marker)

Question 5

What is a common cause of health care associated (nosocomial) infection?

Answer 5

C. difficile

Question 6

What is significant about the virulent strain B1/NAP1/027?

Answer 6

Large amounts of A/B toxin
Binary toxin
Fluoroquinolone resistance

Question 7

What are Actinomyces spp, Bifidobacterium, Propionibacterium, Mobiluncus spp, and Eggerthella classified as?

Answer 7

Gram positive
Non spore forming
Anaerobic Bacilli

Question 8

What is usually considered a contaminant and is associated with serious infections, primarily bacteremia and endocarditis?

Answer 8

Lactobacillus spp.

Question 9

What are the clinical infections of Lactobacillus spp?

Answer 9

Actinomycosis
Bacterial vaginosis

Question 10

What is a chronic, granulomatous disease characterized by sinus tracts and fistulae that erupt to the surface and drain pus that contain dense clumps of sulfur granules?

Answer 10

Actinomycosis

Question 11

What is the most common species of anaerobic bacteria isolated from soft tissue?

Answer 11

B. fragilis