Clinical Psychotic Disorders Dr. Hill Flashcards
positive sx and what phase
delusions, hallucinations, disorganized behavior, catatonia (super hyper they get locked up), agitation
= ACTIVE PHASE
negative sx are what and present in what stage
catatonia, depression, flat face, social withdraw, anhedonia, apathy
= RESIDUAL phase
delirium vs dementias
delirium = acute dementias = longterm, irreversible
disease that expoed during prenatal times that can cause schitzophrienia
Influenza virus
brain parts affected in schitzophrenia
reduced brain V( enlarged 3rd and lateral ventricles)
Reduced limbic system (hippocampus, amygdala), Reduced Thalamus, reduced PFC (causing eventual dementia)
positive sx are associated with what NT
D2 receptors overactivity
GABA low activity
low glutamate
DX schizophrenia how
at least 1 of (Delusions, hallucinations, disorganized speech) and can include grossly disorganized catatonic, negative sx
= need 2 sx or more for 6mo
violent pt give what in ER
Lorazepam or Haloperidol IM
schizophrenia leading cause of death and how to reduce this
suicide (20-50%)
= clozapine can reduce this
catatonia sx and tx
excessive motor activity ( can stand in one place for very long time not eating or moving) repeat what you say involuntary movements excessive negativism = TX with benzodiazepines
antipsychotics do what
block DA receptors
TX :
- acute phase
- stabilized phase
- maintenance phase
- haloperidol, fluphenazine,(FGA) + lorazepam
- SGA
- long acting injections (ROAP)
neuroleptic malignant syndrome
FGA can cause this : fever, muscle rigidity, ANS instability, delirium
Clozapine can cause what side effect
WG
Agranulocytsis
Ziprasidone can cause what side effect
LONG QT