Clinical pharmacy Flashcards

1
Q

What is the first line therapy for acne

A

Benzoyl peroxide
Penetrates skin and enters pilosebasceous unit > free radicle generated > disrupt acne cell walls

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2
Q

What causes acne

A

Excess sebum
Blocked pores
Colonisation of propionibacterium acnes
Inflammation

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3
Q

What are the properties of azelaic acid

A

Comedolytic
Antimicrobial
Anti inflammatory
Anti-keratolytic
Antioxidant
Treat post inflammatory hyperpigmentation

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4
Q

What are the four types of topical retinoids

A

Tretinoin
Adapalene
Trifarotene
Tazarotene

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5
Q

Tetracycline is taken orally while clindamycin is a topical treatment for acne. T or F

A

True.
Tetracycline has bacteriacidal properties
Clindamycin is often taken with BPO

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6
Q

How does oral contraceptive work in acne treatment

A

It reduces ovarian androgen production > increases sex-hormone binding globulin > reduces free testosterone > reducing sebum production

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