Clinical pharmacy Flashcards
What is the first line therapy for acne
Benzoyl peroxide
Penetrates skin and enters pilosebasceous unit > free radicle generated > disrupt acne cell walls
What causes acne
Excess sebum
Blocked pores
Colonisation of propionibacterium acnes
Inflammation
What are the properties of azelaic acid
Comedolytic
Antimicrobial
Anti inflammatory
Anti-keratolytic
Antioxidant
Treat post inflammatory hyperpigmentation
What are the four types of topical retinoids
Tretinoin
Adapalene
Trifarotene
Tazarotene
Tetracycline is taken orally while clindamycin is a topical treatment for acne. T or F
True.
Tetracycline has bacteriacidal properties
Clindamycin is often taken with BPO
How does oral contraceptive work in acne treatment
It reduces ovarian androgen production > increases sex-hormone binding globulin > reduces free testosterone > reducing sebum production