Clinical Neuroanatomy Flashcards
What is the cause of Central Scotoma?
Optic nerve pathology ie optic neuritis, optic nerve compression
What is the cause of bitemporal hemianopia?
Optic chiasm pathology ie pituitary tumour, craniopharyngioma
What is the cause of incongruous homonymous hemianopia?
Optic tract pathology ie pituitary tumour, meningioma
What is the cause of complete macular-splitting homonymous hemianopia?
Optic radiation pathology ie MCA stroke (TACI or PACI)
What is the cause of superior quadrantic hemianopia?
Temporal lobe pathology ie Space-occupying lesion, temporal lobectomy
What is the cause of inferior quadrantic hemianopia
Parietal lobe pathology eg space occupying lesion
What is the cause of homonymous hemianopia (+/- macular sparing)?
Occipital lobe pathology eg occipital lobe infarct or haemorrhage, space occupying lesion
What could cause CN III palsy? What symptoms would be associated?
Aneurysm, diabetes, cavernous sinus lesion, tentorial herniation
Fixed dilated pupil, complete ptosis, all movements paralysed except abduction (VI) and intorsion on down gaze (IV)
What could cause CN IV palsy? What symptoms would be associated?
Head injury
Failure to depress during adduction, positive Bielschowsky test.
(pupil and eyelid normal).
What could cause CN VI palsy? What symptoms would be associated?
Diabetes, idiopathic, raised ICP
Failure of abduction, pupil and eyelid normal
What could cause internuclear opthalmoplegia (INO)?
What symptoms would be associated?
Lesion in median longitudinal fasciculus e.g. MS
Failure of adduction on attempted conjugate gaze, nystagmus in abducting eye, normal adduction on vergence. Painless.
What could cause Parinaud? What symptoms would be associated?
Dorsal midbrain lesion eg pineal tumour
Failure of vergence and vertical gaze (up>down). Fixed dilated pupil.
What could cause ocular myasthenia? What symptoms would be associated?
Thyoma or idiopathic
Fatiguable extraocular movements, painless. Pupil normal but may have ptosis, eyelid fatiguable
When checking pupillary reflexes, what could dilated pupil, small pupil, or RAPD each be signs of?
Dilated - impaired parasympathetic function eg CN III palsy (often marked ptosis)
Small - impaired sympathetic function eg Horner’s (with mild ptosis)
RAPD - optic nerve disease eg MS
How can complete CN III palsy be assessed for?
Dilated pupil, absent light response, accommodation reflex absent.
Brisk construction with 0.1% pilocarpine. Weakness of medial, inferior and superior rectus, and inferior oblique. Complete ptosis.
How can Horner’s syndrome be assessed (eye signs)?
Constricted pupil, normal light response & accommodation.
Failure to dilate with cocaine. Mild ptosis, no extraocular muscle weakness.
How can Holmes-Adie pupil be assessed for?
Dilated with absent light response. Slow, incomplete accommodation response.
Brisk constriction with 0.1% pilocarpine, normal eye movements with no ptosis. Absent tendon reflexes
How can complete Argyll-Robertson pupil be assessed for?
Small irregular pupil, absent light response, no response to atropine. Bilateral ptosis if associated with tabes dorsalis.
How can Holmes-Adie pupil be assessed for?
Dilated pupil, absent light reflex & slow, incomplete accommodation reflex.
Brisk constriction with 0.1% pilocarpine, normal eye movements with no ptosis, absent tendon reflexes
How can Argyll-Robertson pupil be assessed for?
Small, irregular pupil with absent light reflex
Slow accommodation reflex
No response to atropine, bilateral ptosis if associated with tabes dorsalis
For each cranial nerve, which are motor, sensory or both?
I = sensory II = sensory III = motor IV = motor V = both VI = motor VII = both VIII = sensory IX = both X = both XI = motor XII = motor
Severus snape meets malfoy but mad bellatrix stays behind bushes misusing magic
What is the role of CN V? 5
Sensory: ophthalmic, maxillary & mandibular - sensory part of corneal reflex is ophthalmic (Va). (Note: motor corneal reflex = facial nerve)
Motor: mandibular = temporalis, masseter & pterygoids.
What is the role of CN VII? 7
Motor: facial expression muscles & stapedius & chorda tympani (taste anterior 2/3 tongue).
If UMN lesion, frontalis and orbicularis oculi have preserved strength due to BILATERAL innervation.
What is the role of CN VIII? 8
Auditory + vestibular nerves
Assess with Rinne’s (sensorineural vs conductive) and Weber’s test (lateralises to side with conductive loss)
What is the the role of CN IX?
Palatal sensation + afferent for gag reflex
What is the role of CN X?
Motor to palate (elevation) and larynx