Clinical Medicine: Carditis Flashcards
What is acute infective endocarditis?
Staph Aureus
develops on normal heart valve endothelium
fatal in <6wks if not treated
What is subacute infective endocarditis?
less virulent, S. viridans, Enterococcus
develops on damaged heart valve endothelium
fatal >6wks if not treated
What is non-bacterial thrombotic endocarditis
(Marantic endocarditis)
sterile platelet vegetations on cardiac valves
seen in pt’s with metastatic cancer
found on autopsy
may present with new onset murmur
What is non-bacterial verrucous endocarditis
(libman-sacks)
sterile platelet vegetations on cardiac valves
typically seen in patients with SLE
may have new onset murmur
What are risk factors for infective endocarditis?
older age
male
IV drug use (right sided)
poor dentition
structural heart disease
implanted device
What bacteria is the most common cause of right sided endocarditis among IV drug users
S. Aureus
HACEK bacteria include the following and are a small cause of infective endocarditis?
Fastidious g- bacilli
Haemophilus
Actinobacillis
Cardiobacterium
Eiknella
Kingella
What is the classical presentation of infective endocarditis?
Fever
Constitutional sx
new cardiac murmur
vascular embolic events
What are the physical exam findings for infective endocarditis
splenomegaly
petechiae
splinter hemorrhages
osler’s nodes
Janeway lesion
Roth spots
What is he Modified Duke Criteria?
Echocardiography
Blood cultures (must draw before starting abx)
What are the cardiac complications of infective endocarditis?
heart failure
abscess
pericarditis
What are metastatic infections as a result of infective endocarditis?
septic embolization leading to stroke, paralysis, infarct of other organs, PE, etc.
metastatic abscess
meningitis
mycotic aneurysm
osteomyelitis
septic arthritis
What are the renal complications of infective endocarditis?
septic embolization
glomerulonepthritis with renal failure
What is the management for infective endocarditis?
Infectious disease consult and consider Vanc
may need to remove cardiac devices
consider surg. consult for patients with complications
When is endocarditis prophylaxis used?
Only in high risk patients
Hx of infective endocarditis
hx of prosthetic heart valve replacement
hx of cardiac valve repair with prosthetic material
hx of cardiac transplant with valve regurg.
congenital heart disease
before dental procedures
not indicated for GI/GU precedures unless known infection