Clinical Lab Lau Part Deux Flashcards
Which clotting factor is tissue thromboplastin?
III
Which clotting factors are made in the liver?
3, 7, 9, 10 .. think, 1973
Which clotting factors are dependent on vit. K?
3, 7, 9, 10 - same as those made in liver - duh!
occurs in people who have sickle cell disease when large numbers of sickled red blood cells become trapped in the spleen, causing it to suddenly enlarge. causes death within a matter of hours
splenic sequestration crisis - will severely drop your platelet count
which commonly taken medications (OTC) will cause thrombocytopathy?
NSAIDS, salicylates
What are the two tests used for anticoagulant control?
PT, and aPPT
used to determine the clotting tendency of blood, in the measure of warfarin dosage, liver damage, and vitamin K status.
INR (PT)
partial thromboplastin time (PTT) or activated partial thromboplastin time measures which pathway?
intrinsic
aPTT is used to measure which anticoagulant?
heparin
What are the tests used for preprocedure homeostasis screening?
aPTT, and PT
what is antidote for heparin OD?
protease sulfate - this slows down the proliferation of heparin
what is the antidote for Coumadin OD?
vit K
what function test should be run before conducting a bleeding time test?
liver function test
which clotting test is performed in evaluating patients with severe liver disease?
PT
in general, happens to esr as age increases?
increases - normal 15|20 male|female; over 50 20 and 30 respectively
an inflammatory disorder that causes muscle pain and stiffness.
Polymyalgia rheumatica
what is the diagnostic test used for temporal arteritis?
ESR - Giant-cell arteritis (GCA or temporal arteritis or cranial arteritis) or Horton disease is an inflammatory disease of blood vessels most commonly involving large and medium arteries of the head, predominantly the branches of the external carotid artery. It is a form of vasculitis. common sequela is blindness.
male comes in with possible dx of anemia - what are the first three tests that should be performed?
guaiac, colonoscopy, and endoscopy
male comes in with possible dx of anemia, he has a hx of alcoholism, what do you want to check?
mcv - might have macrocytic anemia
male comes in with possible dx of anemia, patient is over 55 what is most likely cause?
cancer
male comes in with possible dx of anemia, in his early 20s - what is most likely cause?
ulcerative colitis or crohn’s
typical first line treatment for Menorrhagia?
BCP
typical second treatment for Menorrhagia?
steroid or NSAID
