Clinical Disease Repro Tract Dog and Cat Flashcards
What are the common reproductive diseases affecting the ovary, uterus and vagina in the dog and cat?
Ovarian Neoplasia
Pyometra, Mucometra
Dystocia
Vaginal Hyperplasia/prolapse
Vaginal neoplasia
Vaginal trauma
Ambiguous genitalia
What is important to know about vulvar discharge when examining female patient?
Color
Whether its coming from uterus or urethra
Stage of reproductive cycle (diestrous, pregnancy)
What are the causes of creamy white vulvar discharge?
Vaginitis
Early metestrous
Open pyometra
What are the causes of bloody vulvar discharge?
Proestrous
Estrous
Persistent ovarian follicle
Ovarian tumor (estrogen-secreting)
Vaginal trauma
Vaginal FB
Cystitis
Urethral neoplasia
Coagulopathy
Placental separation
Sub-involution post partum
Vascular malformation
What are the causes of clear mucoid discharge?
Normal
What are the causes of clear watery discharge?
Amniotic/alantoic fluid
What are the causes of greeny black discharge?
Normal parturition
Dystocia
What are the causes of Brown/Red –> Black discharge?
Metritis
What are the causes of yellow discharge?
Incontinence
What is vaginitis?
Inflammation of the vagina
How does vaginitis usually present in the bitch?
Purulent discharge
What is the difference between juvenile and adult vaginitis?
Juvenile (prepubertal) vaginitis
- Secondary to bacterial contamination and excess vaginal secretion
- Usually resolves spontaneously with first season
- Do not give ABX
Adult vaginitis
- Less common, aim to ID cause and treat
- May respond to exogenous estrogens (topical/oral)
What is pyometra? What animals does this affect?
Uterus fills with pus, can result in life-threatening illness (treat as emergency)
Affects both dogs and cats
What is the difference between open and closed pyometra?
Open - cervix associated with mucopurulent vaginal discharge and a mild-moderately enlarged uterus
Closed - cervix not associated with vaginal discharge, uterus is usually grossly enlarged and animal systemically ill
How many weeks within the last estrous does pyometra usually present?
Within 8 weeks
What are the factors which increase the risk of an animal developing pyometra?
Cystic endometrial hyperplasia
Bacterial infection (E. coli)
Progesterone
Open Cervix
What are the common clinical signs associated with pyometra?
Depression, lethargy, mucopurulent vaginal discharge (open), pyrexia, PU/PD, vomiting, collapse, shock
What are the common pathological changes you will see with pyometra (Bloodwork)?
Neutrophils with left shift (degenerate)
Possible azotemia (renal)
Acidosis
Endotoxemia
Hypyglycemia
Anemia
Coagulopathies
How do you diagnose pyometra?
Ultrasound or radiography
How do you commonly treat pyometra?
Surgical - most common (OVH)
Medical - recurrence possible, reserved for dogs with breeding value
How common is vaginal trauma? How does this usually happen?
Uncommon - usually iatrogenic (Ex. perforation during contrast study)
Forced separation of mating dogs
Malicious wounding (welfare issue)
How should you investigate/treat vaginal trauma?
Confirm origin of bleeding
Provide conservative/supportive treatment (usually all that is required until bleeding stops)
What is happening here? (Hint - vagina)
What is happening here? (Hint - vagina)
What are the most common tumors in the bitch?
Smooth muscle tumor of vagina/vestibule - leiomyoma/leiomyosarcoma (slow growing smooth muscle tumor)
What is the typical signlament of dogs presenting with vaginal neoplasia? What are the clinical signs?
65% bitches entire, usually elderly
May present with visible mass, bulging perineum or dysuria/dyschezia
How do you diagnose vaginal/vestibular neoplasia?
History/PE
Endoscopy
Radiography
Biopsy
What is the treatment for vaginal/vestibular neoplasia?
Surgical excision of mass + OVH
Chemotherapy - option for some tumors
How does vaginal edema/prolapse occur?
Excessive response of vaginal mucosa to estrogens during follicular phase of estrous cycle = vaginal edema (hyperplasia) and vaginal prolapse
Which breeds are predisposed to vaginal edema/prolapse?
Brachycephalics
What is important to check before reducing prolapsed vaginal tissue?
Check for lesions as exposed tissues may get traumatized
How do you diagnose and treat vaginal edema/prolapse?
Diagnose through history and PE
Majority of treatment is conservative (keep moist, place sutures)
Surgical excision (episiotomy)
How common is recurrence of vaginal edema/prolapse? What can you do to reduce chances of recurrence?
Common (tends to recur)
Must control estrous and recommend neuter
What is ambiguous genitalia a manifestation of? What does it indicate?
Intersexuality
Indicates presence of androgens and therefore testicular material +/- ovarian tissue
How do you investigate ambiguous genitalia?
What is the management for ambiguous genitalia?
Removal of gonads
Possible partial penis amputation/removal of penis via episiotomy
Treatment of other abnormalities if associated with other clinical signs
What is dystocia?
Disturbance during parturition when normal delivery of fetus through birth canal is interrupted
Is dystocia more common in the dog or the cat?
Dog
What are the 3 factors involved in dystocia?
Maternal
Maternofetal
Fetal
What are causes for concern during parturition (signals that you might need to intervene)?
What are the maternal causes for dystocia?
What is the most common cause for dystocia?
Maternal - Uterine inertia
What are the fetal causes for dystocia?
Fetal malpresentation
Increased fetal size
- Increased size, litter number, gestational length, genetic/breed factors
Abnormal fetal development
- Hydrocephalus, other congenital abnormalities, fetal death
What is the most common cause of fetal dystocia?
Fetal malpresentation
Fetal oversize (brachycephalics over-represented)
What is uterine inertia? How is it classified?
Uterine muscle is unable to contract and expel fetus
Primary - uterus fails to respond to fetal signals
Secondary - exhaustion of myometrium, secondary to obstruction in birth canal
What are the most common causes of primary uterine inertia?
Small litter, large litter
Systemic disease
Obesity, age, nutritional imbalance
Inherited predisposition