Clinical Chemistry: Maam Peewee Lecture Notes Flashcards

1
Q

Base quantity and their based units

A

“LTM TALE”

Length = meter
Time = seconds
Mass = kilogram
Temperature = Kelvin
Amount of substance = mole
Luminosity = Candela
Electric Current = Ampere

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2
Q

All of the base quantities are expressed in based unit except for:

A

Mass —> kilogram

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3
Q

Enzyme assay base unit
KATAL= _______
International Unit = _______

A

KATAL = mol / L / sec
International Unit = umol / min / L

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4
Q

Enumerate the prefixes and their corresponding factors:

A

exa = ^18
peta = ^15
tera = ^12
giga = ^9
mega = ^6
kilo = ^3
hecto = ^2
deka = ^1
deci = ^ -1
centi = ^ -2
milli = ^ - 3
micro = ^ -6
nano = ^ -9
pico = ^ -12
femto = ^ -15
atto = ^ -18

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5
Q

Factor for prefix femto

A

10^-15

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6
Q

Factor for prefix mega

A

10^6

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7
Q

Factor for prefix milli

A

10^-3

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8
Q

Analytes with 1 as their conversion factor

A

“Bi CLOPS”

Bicarbonate
Chloride
Osmolality
Potassium
Sodium

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9
Q

Analytes with 10 as their conversion factor

A

“ HAT “

Hemoglobin
Albumin
Total Protein

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10
Q

Conversion factors of:
Glucose
Uric Acid
Ammonia
Magnesium

A

“GUAM”

Glucose = .0555
Uric Acid = .0595
Ammonia = .587
Magnesium = .5

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11
Q

Conversion factors of:
Thyroxine (T4)
Bilirubin
Folic Acid
Creatinine

A

“The Big Fat Cock”

Thyroxine (T4) = 12.9
Bilirubin = 17.1
Folic Acid = 2.27
Creatinine = 88.4

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12
Q

Conversion factor of:
Triglycerides
Cholesterol
BUN

A

Triglycerides = .0113
Cholesterol = .026
BUN = .357

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13
Q

Conversion factors of:
AST
Creatinine Clearance
Cortisol
Vit. B12
Iron
Calcium
Phosphorus

A

“ACC to VIC P”

AST= .0167
Creatinine Clearance = .0167
Cortisol = .0276
Vit. B12 = .0738
Iron = .179
Calcium = .25
Phosphorus = .323

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14
Q

Conversion factor of Albumin

A

10

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15
Q

Conversion factor of bilirubin

A

17.1

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16
Q

Conversion factor of BUN

A

0.357

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17
Q

Conversion factor of Chloride

A

1

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18
Q

Conversion factor of Cholesterol

A

0.026

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19
Q

Conversion factor of Creatinine

A

88.4

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20
Q

Conversion factor of Creatinine Clearance

A

0.0167

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21
Q

Conversion factor of Glucose

A

0.0555

22
Q

Conversion factor of lithium, potassium, sodium

A

1

23
Q

Conversion factor of Uric Acid

A

0.0595

24
Q

BUN representation of urea measures the _____ content

A

Nitrogen

25
Q

BUN to Urea conversion factor

A

2.14

26
Q

Urea to BUN conversion factor

A

0.467

27
Q

Convert 5.5 g to mg

A

5,500 mg

28
Q

Convert 555 mm to m

A

0.555

29
Q

Grade of a particular chemical is dependent on the ______ of chemical

A

Purity

30
Q

Grade of Purity of Analytic Chemicals is established by _______.

A

American Chemical Society (ACS)

31
Q

Type of reagent suitable for most of analytical laboratory procedures, and second purest

A

Analytic Reagent

32
Q

Put through additional purification steps —> extremely pure chemicals, and is the purest of the pure, and is for special procedures like HPLC (High-Performance Liquid Chromatography)

A

Ultrapure

33
Q

Used for manufacture of drugs (medicine); sole criterion is should not be injurious to individuals; may be pure enough for used in medical (chemical) procedures; and is not based on the needs of the laboratory

A

United States Pharmacopeia (USP)

34
Q

Type of analytic chemical used in manufacturing; should never be used in clinical laboratories

A

Technical or Commercial Grade

35
Q

Grading system of analytic chemicals is established by ______.

A

International Union of Pure and Applied Chemistry (IUPAC)

36
Q

Grading A in the grading system by IUPAC

A

Atomic Weight Standard

37
Q

Grading B in the grading system by IUPAC

A

Ultimate Standard

38
Q

Grading C in the grading system by IUPAC

A

Primary Standard

39
Q

Grading D in the grading system by IUPAC

A

Working Standard

40
Q

Grading E in the grading system by IUPAC

A

Secondary substances

41
Q

Most highly purified chemical or reagent that can be measured directly in order to produce of exact purity; tolerance level is 100 +/- .02 %; 99.98 % pure, but not applicable to laboratory

A

Primary Standards Reagent

42
Q

Used in the laboratory, NIST certified standard materials in place of primary standards; it is utilized by manufacturers in order to produce calibrators and standard materials utilized in the laboratory

A

Standard Reference Material

43
Q

Lower purity compared to primary standard

A

Secondary Standard

44
Q

Grades of water
- Highest; utilized in procedures that require maximum water purity like standard solution preparation, ultramicrochemical analyses measurements at nanogram or subnanogram, and tissue and cell cultures

A

Type I

45
Q

Used for most laboratory methods; for quantitative and qualitative determinations in CC,, HEMA, MICRO, IMMUNOSERO and other chemical laboratory areas

A

Type II

46
Q

Used for qualitative measurements only; most procedure in Urinalysis, PARA, and HISTO; and is used for washing glasswares

A

Type III

47
Q

Parts er hundred or amount f solute per 100 total units of solution

A

Percent Solutions

48
Q

Most common expression of concentration as to percent solution

A

Weight per volume (w/v)

49
Q

Molarity Formula

A

M = mol of solute / L of solution

50
Q

Molality Formula

A

m = moles of solute / kg of solution

51
Q

Normality Formula

A

N = gram equivalent weights / Liter of solution