Clinical Approach to Headache Flashcards
What is needed for headache history?
- Good general health history
- Headache history –> Types, frequency
- Pain –> intensity/quality, location, duration, impact of exertion
- Prodrome
- Associated symptoms
- Behavior –> retreats to dark, quiet room, paces, rocks
- Triggers
- Current or previous medications tried
What are some prodromes that may be seen in headaches?
- Change in energy levels, mood, appetite
- Fatigue
- Muscle aches
- Aura
What is needed in the medical or surgical history when looking into headaches?
- Comorbidities –> sleep disturbances and mood disturbances
- Other medications
- Head trauma
- Previous LOC
- Seizure disorders
- Allergies
What is needed about family/social history when looking into headaches?
- Family illnesses, including headaches
- Habits –> smoking, alcohol, other drugs
- Occupation
What should be part of the physical exam when looking into headaches?
- Vital signs –> particularly BP/pulse
- Cardiac status
- Extracranial structures
- ROM and presence of pain in C-spine
What should be included in the neurological exam for headaches?
- Neck flexion
- Presence of bruits over the head and neck
- Optic fundi, pupils, visual fields
- Thorough cranial nerve exam
- Motor power in limbs
- Muscle reflexes
- Plantar responses
- Sensory exam
- Coordination
- Gait
What are some worrisome signs in a headache?
- Worst headache
- Onset of headaches after age 50
- Atypical headache for patient
- Headache with fever
- Abrupt onset
- Subacute headache with progressive worsening over time
- Drowsiness, confusion, memory impairment
- Weakness, ataxia, loss of coordination
- Paresthesias/sensory loss/paralysis
What is meningitis?
- Inflammation of the meninges surrounding brain and spinal cord, sometimes with associated encephalitis
What is the most common cause of meningitis in adults, infants, and young children?
- Strep pneumoniae
What is the most highly contagious cause of meningitis?
- N. meningitidis
- Seen in young adults and teenagers
What are some complications of bacterial meningitis?
- Hearing loss
- Memory difficulty
- Learning disabilities
- Brain damage
- Gait problems
- Seizures
- Kidney failure
- Shock or death
What are the symptoms of meningitis in people over 2 years old?
- Sudden high fever
- Stiff neck
- Severe headache that seems different than normal
- Headache with N/V
- Confusion or difficulty concentrating
- Seizures
What are the signs of meningitis in newborns?
- High fever
- Constant crying
- Excessive sleepiness or irritability
- Inactivity or sluggishness
- Poor feeding
- Bulge in the soft spot on top of baby’s head
- Stiffness in a baby’s body and neck
What should be given to infants and children with bacterial meningitis?
- Empirical antibiotics and steroids which helps prevent from long term complications
What does CSF look like in bacterial meningitis?
- Opening pressure –> elevated
- WBC –> ≥1000 per mm3
- Cell differential –> PMNs
- Protein –> mild to moderate elevation
- Glucose –> normal to marked decrease
What does CSF look like in viral meningitis?
- Opening pressure –> normal
- WBC –> <100 per mm3
- Cell differential –> Lymphocytes
- Protein –> normal to elevated
- Glucose –> normal
What does CSF look like in fungal meningitis?
- Opening pressure –> variable
- WBC –> variable
- Cell differential –> lymphocytes
- Protein –> elevated
- Glucose –> low
What are some common causes of infectious encephalitis?
- HSV 1 or HSV 2
- West Nile
- Varicella Zoster
- Treponema pallidum
What are some causes of infectious encephalitis in neonates?
- HSV2
- CMV
- Rubella
- Listeria
- Treponema
- Toxoplasma
How does HSV 1 encephalitis present?
- Rapidly progressive neurologically devastating illness with combination of fever, headache, impaired consciousness, seizures, and focal neurologic symptoms
What do MRI and EEG show in HSV1 encephalitis?
- Focal abnormalities in temporal lobes
What is the treatment for HSV1 encephalitis?
- Acyclovir
What can happen do people who recover from HSV 1 encephalitis?
- Could develop recurrent neuropsychiatric symptoms sometimes associated autoantibodies with secondary autoimmune encephalitis
What are some treatment options for autoimmune encephalitis?
- High dose steroids
- IVIG
- Plasma exchange
- Rituximab
- Cyclophosphamide
Who is affected by NMDA encephalitis?
- Young or middle aged women
How does NMDA encephalitis present?
- Abnormal psychiatric behavior or cognitive dysfunction
- Speech dysfunction
- Seizures
- Movement disorders, dyskinesias, or rigidity/abnormal postures
- Decreased LOC
- Autonomic dysfunction or central hypoventilation
What is seen on laboratory study in NMDA encephalitis?
- Abnormal EEG –> extreme delta brush (diagnostic)
- CSF with pleocytosis or oligoclonal bands and/or NMDA receptor antibodies
What is associated with NMDA encephalitis?
- Presence of teratoma