Clinical - Antibiotics & Infections

Question 1

What is the purpose of using APACHE II when selecting an antimicrobial agent?

Answer 1

focusses on patient factors

Question 2

What is the purpose of using BRASS when selecting an antimicrobial agent?

Answer 2

focuses on criteria for potential drug to be used

Question 3

What does APACHE II stand for?

Answer 3

A - age + gender
P - pregnancy + breastfeeding
A - antibiotic exposure
C - cautions + contraindications
H - hypersensitivity
E - elimination (PK)
I - immunity
I - interactions

Question 4

What does BRASS stand for?

Answer 4

B - bioavailability
R - resistance
A - access to site of infection
S - spectrum of activity
S side effects

Question 5

What is the purpose of using PS when selecting an antimicrobial agent?

Answer 5

focuses on infection itself

Question 6

What does PS stand for?

Answer 6

P - pathogen
S - severity

Question 7

What is the purpose of using FROGS when selecting an antimicrobial agent?

Answer 7

considers social factors

Question 8

What does FROGS stand for?

Answer 8

F - formulary
R - restricted list of antibiotics
O - organisational policies
G - guidelines on empirical Tx
S - selective reporting of antibiotic sensitivities