Clinical Antibiotic Use Flashcards
What utility is associated w/ specimen collection? Pitfalls?
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What are some important points to keep in mind when obtaining appropriate specimens?
- Infecting orgs should be obtains BEFORE the start of therapy
- Tissues/fluids needs for cultures — NOT swabs
- Deeper specimens preferred over superficial
- Don’t culture fluid from a drain UNLESS it was just freshly placed
- Remember it’s volume dependent! plus bacteria doesn’t live long on swabs
- The gram stain is your friend (you will first know if a org is G(+) or G(-) and its shape before the actual org)
Describe the principles involved during empiric antibiotic use
THINK:
1) What is the infectious syndrome? Where is it located?
2) What are common pathogens that may cause this syndrome?
3) What is the likely resistance associated with the organisms being considered?
4) What’s the most appropriate antibiotic to use?
What are the methodologies used for antibiotic susceptibility testing?
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Describe the importance of antibiotic susceptibility testing
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Describe MIC
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Describe MBC
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Describe MIC and MBC’s important in determining antibiotic susceptibility
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Describe MIC and MBC’s important in defining bactericidal/bacteriostatic antibiotic activity
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What are the antibiotic susceptibility categories?
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Describe the antibiotic susceptibility category A’s caveats and principles invovled in setting interpretive breakpoints
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Describe the antibiotic susceptibility category B’s caveats and principles invovled in setting interpretive breakpoints
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Describe the antibiotic susceptibility category C’s caveats and principles invovled in setting interpretive breakpoints
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Describe the antibiotic susceptibility category D’s caveats and principles invovled in setting interpretive breakpoints
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Describe how local factors contribute to appropriate antibiotic selection
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