Clinical Flashcards
What are the 4 things on XRay that will be seen in a to with pulmonary hypertension
1) Peripheral hypovascularity
2) Prominent central pulmonary artery
3) Right ventricular enlargement
4) Right descending pulmonary artery
What is the cause of Pulmonary Hypertension group 1
Idiopathic and chronic tissue diseases (SLE or RA)
What is the cause of Pulmonary Hypertension group 2
Heart issues
What is the cause of Pulmonary Hypertension group 3
Lung issues
What is the cause of Pulmonary Hypertension group 4
Emboli and thrombi
What is the cause of Pulmonary Hypertension group 5
Everything else
Similarities between pulmonary hypertension and ischemic heart disease
- Exertional dyspnea
- Lack of associated symptoms
- Elevation of BNP
Which condition is indicated with an elevated P2 during auscultation
Pulmonary hypertension
What are the patient history clues that can lead to diagnosis of sleep apnea
- Motor vehicle accidents
- Difficulty with memory
- Obesity with depression
- Snoring
- Witnessing apnea
- Large neck circumference
- Nasal obstruction (nasal polyps)
- Enlarged tonsils
People with obstructive sleep apnea are at increased risk for which conditions
- Cancer (2.5x)
- Cerebral vascular aneurysm (4x)
How does a CPAP work
Increases the intraluminal airway pressure and FRC to keep the airways open
What is the pockeickian syndrome
Aka obesity hypoventilation syndrome, where being overweight leads to appearance of COPD and other issues such as CHF and CAD
*Most have restrictive rather than obstructive lung issues
What is the responsiveness to carbon dioxide in the pink puffer and the blue bloater
Blue bloater is unresponsive to carbon dioxide
Pink puffer is responsive to carbon dioxide, so makes the hyperventilate to breathe off the excess
What are the indications home supplemental oxygen
-PaO2 <56 or 89% measures twice over 3 week period
-Pa)2 from 56-60 with:
Pulmonary HTN
CHF
Erythrocytosus >55%
If you have a patient with pulmonary fibrosis presenting with low pleural glucose, what is the likely entity
RA
When a patient presents with interstital lung disease with “shrinking lung” where the volumes keep decreasing, what is the underlying entity
SLE
What is the autoantibody seen in scleroderma that will commonly be seen with interstital lung disease
SCL-70
What is the autoantibody present in scleroderma that is predicts a worst prognosis
Antinucleolar
What autoantibody is present in SLE that correlates with nephritis
DsDNA (50-75%)
What is the most common autoantibody seen in SLE
ANA (90-95%)
What is the autoantibody that is present in those patients with drug induced SLE
Histones (>90%)
What are the common drugs that can lead to induced lung disease
- Amioderone (treats cardiac issues)
- Nitrofurantoin (treats UTI)
- Bleomycin (treats germ line tumors such as testicular)
- Busulfan (restrictive lung disease)
What are the drugs that are given/used for a patient with idiopathic pulmonary fibrosis
- Pirfenidone
- Nintedanib
This individuals who enjoy cave diving are known to have inhalation of which chemicals
Silica and bat guano
What conditions of the lung is commonly seen to have a pattern on chest X-ray that is diffuse, symmetrical, and bilateral
Acute interstital pneumonia
What is the combination of symptoms leading to the idea of Sarcoidosis
- Erythema nodosum
- Fever
- Arthralgia
- Hilar adenopathy (on CXR) usually bilaterally
What conditions is lymphangioleiomyomatosis associated with
Tuberous sclerosis
Most patients pediatric emergency arrests are due to which issue
Respiratory