Clinical Flashcards
what are the 4Ds
-defiance
-dysfunction
-distress
-danger
what is deviance?
those behaviours which re unusual, undesirable and bizarre. social norm statistics are gathered through age, gender, culture etc. and failure to conform to these norms shows psychological abnormality.
what is dysfunction?
symptoms which distract, confuse or interfere with a persons ability to carry out their usual roles and responsibilities. can been seen as trouble getting up in the morning. measured through a questionnaire looking at a persons understanding on what is going on around them called WHODAS II.
what is distress?
symptoms that cause emotional pain or anxiety, showing a diagnosis may be beneficial for this person. distress may be manifested as physical symptoms. distress will be looked at through a 10-item self-report questionnaire called the K10 to get an appropriate diagnosis.
what is danger?
careless, hostile or hazardous behaviour which jeopardises the safety of the individual. if someone is seen to be a danger they can be detained through the mental health act which requires agreement from 3 professionals.
strengths of the 4Ds
- all 4 can be used together to help avoid errors in diagnosis. this is important because a valid system needs to be neither over or under-inclusive.
- 4Ds are used in conjunction with classifications manuals such as the ICD or DSM. different disorder tend to display different combinations of Ds, meaning each of the 4Ds are used in diagnosis.
weaknesses of the 4Ds
- they don’t lend themselves to objective measurement. lack of objectivity affects reliability. individuals are compared to society but it would be better if they were compared to a reference, control group. the clinician require detailed on the individual and their wider community to use the 4Ds meaningfully.
- we end up with labels for people with mental issues. Fazel (2009) people with schizophrenia aren’t more dangerous than people without the diagnosis. attitudes may become self fulfilling prophecies, stereotypes lead to people acting in the way they are stereotyped.
symptoms of schizophrenia
- thought insersion
- hallucinations
- delusions
- disordered thinking
features of schizophrenia
- lifetime prevalence is 0.3-0.7
- onset is earlier in males mid 20s and late 20s for females
-prognosis hard to predict
whais neurotransmitters as an explanation of schizophrenia?
- excess dopamine (hyperdopaminergia)
- dopamine deficiency (hypodopaminergia)
- serotonin causing negative symptoms
- dopamine dysregulation (striatum being the pathway to psychosis)
what is hyperdopaminergia?
high levels of dopamine due to two reasons:
-low levels of beta hydrolyse- enzyme which breaks down dopamine, causing excess in synapse.
- proliferation of D2 dopamine receptors being responsible for hyperdopaminergia activity.
what is hypodopaminergia?
davis et al (1991) suggests that positive symptoms of schizophrenia (delusions, hallucinations, thought insertion, disordered thinking) are from excess dopamine in the mesolimbic pathway. negative symptoms (flat effect) are from hypodopaminergia in the mesocortiyal pathway.
what is serotonin causing negative symptoms?
clozapine binds to serotonin receptors and reduces positive and negative symptoms. hypothesis that negative symptoms are caused by irregular serotonin activity. serotonin also regulates dopamine levels.
what is dopamine dysregulation?
Howes and Kapur (2009) states dopamine dysregualation in the striatum as the common pathway to psychosis
strengths of neurotransmitter explanation of schizophrenia
- tenn et al (2003) found that rats given 9 amphetamine injections over three weeks showed various schizophrenia like symptoms. dopamine antagonists were successful in reversing these effects. shows increased dopamine levels cause schizophrenia symptoms.
- snyder (1985)- chlorpromazine acts as an antagonist at many doopamine receptors especially D1 and D2. Haloperidol is a dopamine antagonist with narrower range of biochemical effects yet more effective. this shows that excess activity of specific not all receptors causes development of schizophrenic symptoms.
- effective drug treatments- haloperidol reduce positive symptoms, clozapine reduces both positive and negative symptoms