Clin Med 2 Flashcards

1
Q

when taking bp, initial measurements should be taken on which arm? nml diff = 5-10mmHg, but what’s abnl?

A

both. 10-15mmHg -> subclavian steal syndrome, aortic dissect

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2
Q

when to do more invasive testing for bp? when giving meds, how much bp reduction should you aim for?

A

refractory HTN, sus for secondary causes, new sudden onset. reduce slowly -> 5-10mmHg/wk

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3
Q

what’s cyanosis? physio vs patho?

A

blue skin & mucosa d/t deO2/reduced hgb. when cold, blood = shunted to internal organs vs blood flow obstruction from a/v thrombosis, embol, vasospasm, external compression

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4
Q

what 3 sxs determine thrombosis?

A

Virchow’s triad: impaired blood flow/stasis, vasc endothel dmg, hypercoag (acquired ab, mutations, iatrogenic)

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5
Q

primary vs secondary hemostasis

A

phospholipase frees arachidonic acid from cell mem –> arach acid to TX –> degran –> PLT bind to vasc wall via collagen, vWF vs coag cascade, thrombin making fibrin clot, fibrinolytics to stop making clot

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6
Q

L vs R side heart fail PE findings. aortic stenosis PE findings

A

rales, S3, displaced PMI vs ascites, edema, JVD. systolic murmur, abnl pulses

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7
Q

LV dysfxn vs RV infarct

A

cardiogenic shock -> inc HR for dec CO, rales & edema –> IABP, impella; diuretics, other antiHTN; inotropic/pressor, DA/dobutamine, dobutamine/phenylephrine; ECMO/LVAD vs no rales but HoTN –> lg vol fluid, reperfusion, time

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8
Q

inf infarct = ischemia of? complete AV block occurs from?

A

SA node -> sinus brady, AV node -> AV block. ant MI < inf MI < pre-existing RBBB + LAFB

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9
Q

most serious electrical complication of ACS is? do we tx accel idio vent rhythm? how to avoid these complications? how to tx brady vs tachycardia?

A

vtach/vfib -> defib & CPR, amiodarone. no. be prepare, correct electrolytes, keep hgb in optimal range. atropine, pace vs BB, CCB

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10
Q

what to do for initial eval for VHD? additional eval?

A

H&P: EKG & CXR -> heart size, pulm congst, intrinsic lung dz, calc of aorta or pericardium; TTE = most accurate way to assess VHD. TEE for mitral or prosthetic valve, intracardiac mass; cardiac cath for intracardiac & pulm pressure, valve severity, hemodynamic response to exer & drugs; CMR, PET-CT, exer test

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11
Q

what are the 4 preprocedural tests you need before valve intervention?

A

dental exam to prevent bacteria; CT coronary angio for coronary aa anatomy; CT periph for fem access for TAVI; CT cardiac for suitability of TAVI

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12
Q

stage A vs B vs C vs D of VHD

A

at risk vs progressive -> mild/mod, asx vs asx severe; C1 = L/RV compensated, C2 = L/RV decompensated vs sx severe

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13
Q

when to follow up for pts w/ VHD?

A

if no new/changing sxs -> rpt TTE
Stage B = f/u q 3-5y for mild, 1-2y for mod
Stage C = f/u q 6-12mo x/ mitral sten -> 1-2y

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14
Q

managing pts after valve intervention: procedure complications vs management vs sxs after intervent

A

paravalvular leak, bleed, stroke vs endocarditis prophylaxis, routine echo vs INR if VKA anticoag, assess valve fxn

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15
Q

img after valve intervention: mechanical vs bioprosthetic vs mitral valve repair

A

baseline echo (tradeoff = lifelong anticoag like warfarin) vs baseline echo, 5-10yrs post op, then annual (doesn’t last long) vs baseline echo, 1 yr, then 2-3yrs (clot can form in mitral valve)

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16
Q

how to manage acute decompensated heart fail vs chronic compensated HRrEF vs chronic compensated HR pEF

A
  1. identify cause
  2. resp support -> nasal cannula, biPAP, invasive mech vent; cardiogenic shock -> inotropes, intraaortic balloon pump, LVAD, ECMO
  3. tx fluid overload w/ IV diuretics
  4. BB, ACE/ARB/ARNI, aldost antag, loop diuretic prn SLGT2 inhib
    vs
    valsartan-sacubritril > BB > aldost antag > SLGT2 inhib for class II-IV sxs; implantable cardiovert defib (40d post MI & 3mo post other causes), & cardiac resync therapy for NYHA II-III & EF<35% despite meds -> pace RV apex & LV lat wall via coronary sinus & lat cardiac v vs diuretics’, antiHTN, SLGT2 inhib