Clicker Questions

Question 1

What is true regarding characteristics of heterochromatin?
A. Loosely packed; active
B. Loosely packed; inactive
C. Tightly packed; active
D. Tightly packed; inactive
E. Heterochromatin stays at a constant compaction and is always inactive

Answer 1

D. Tightly packed; inactive

Question 2

In which of the following situations would a DNA helicase be recruited to assist with repair?
A. Deaminated C
B. Purine Dimer
C. Pyrimidine Dimer
D. Unnatural base detection
E. Methylated cytosine

Answer 2

C. Pyrimidine Dimer

Question 3

What is the role of glycosylase in DNA repair and which repair pathway is it involved in?
A. Scans DNA for distortion; nucleotide excision
B. Scans DNA for distortion; base excision
C. Fills in the missing sugar groups once mutation is removed; nucleotide excision
D. Flips out bases looking for errors; nucleotide excision
E. Flips out bases looking for errors; base excision

Answer 3

E. Flips out bases looking for errors; base excision

Question 4

What is the role of RecA in homologous recombination?
A. Allows single strand DNA binding to double stranded DNA
B. inhibits homologous recombination anytime other than during S and G2 of cell cycle
C. Checks for double stranded breaks during checkpoints of cell cycle
D. Acts as polymerase during homologous recombination
E. Seals the newly synthesized strands together once repair is complete

Answer 4

C. Checks for double stranded breaks during checkpoints of cell cycle

Question 5

Which RNA polymerase transcribes DNA?

Answer 5

RNA polymerase II

Question 6

Which polymerase transcribes ribosomal RNA?
A. RNA polymerase I
B. RNA polymerase II
C. RNA polymerase III
D. A, C and B
E. DNA dependent RNA polymerase

Answer 6

D. A, C and B

Question 7

Abnormally large RNA transcripts are produced. What may be the cause?
A. overactive PAP
B. Inactive CPSF and CstF
C. Intron mutations
D. all of the above

Answer 7

D. all of the above

Question 8

MicroRNAs have tremendous potential for disease intervention in nearly all cases where stopping gene activity would be valuable. Which of the following are potential causes for concern for use of miRNAs for therapeutic intervention?
A. Precise delivery to tissue of significance
B. off target interactions
C. mutation of immune response goes
D. mutation of oncogenes
E. all of the above
F. A and B

Answer 8

E. all of the above