Clicker Questions Flashcards
Which of these polymerases does NOT transcribe rRNAs and tRNAs?
A. RNA pol I
B. RNA pol II
C. RNA pol III
D. Bacterial RNA
polymerase
B. RNA pol II
What would be the consequence of a null
mutation in the guanylyltransferase that caps
the mRNA?
mRNAs would not
be translated
Which one of these genes has the highest transcription rates?
RecA
If the coding strand is the following sequence,
what is the mRNA sequence?
5’ ATGCAGTCCATA
5’ AUGCAGUCCAUA
If the template strand is the following sequence,
what is the mRNA sequence?
5’ ATGCAGTCCATA
3’ UACGUCAGGUAU
What would be the consequence
of a null mutation in TFIIH?
open complex does
not form
Which of the following is not a difference
between prokaryotic and eukaryotic
transcription?
open complex formation
precedes elongation
Which of the following mutations would most
likely happen if you got an x-ray without a lead
shield?
chromosomal break
What mutagen most commonly
causes thymine dimers?
sunlight
What would be the consequence
of a mutation in MutH?
Increased mutations
after DNA
replication
What kind of mutation commonly
occurs after NHEJ
small deletions
What type of mutation is shown in the following:
5’ ATGCAGTTTAAG
5’ ATGCAGATTTAAG
frameshift
What type of mutation is shown in the following:
5’ ATGCAGTTTAAG
5’ ATGCAGTTCAAG
silent
Which of these mutations would
likely have the most severe impact on the phenotype?
mutation in splice
junction
If this sequence has deamination of 5mC, what would be the resulting mutation?
5’ – ATGCCGTAT -3’
missense
Which of these elements require
transposase to move?
Insertion elements
Simple transposons
What would be the consequence of a nonfunctional DNA ligase during DNA replication?
Single-stranded breaks in
DNA would be present
Which of the following is a difference between prokaryotic and eukaryotic DNA replication?
Ends replication problem
Flap endonuclease
Experimental results support which model(s) for initiating recombination during meiosis and DNA repair?
DNA double strand breaks (DSB)
Which pair of proteins is required for nucleotide excision repair (NER)?
UvrC and DNA ligase
Double-strand breaks are typically repaired by which of the following?
nonhomologous end joining and homologous recombination repair
Bases which exist in keto and enol or amino and imino forms are best described as ______.
tautomers
Alkylating agents include nitrogenBlank 1 gas and ethyl Blank 2 (EMS).
mustard
methanesulfonate
Proflavin is best described as a(n) ______ agent.
intercalating
