Classification Of Protozoa Flashcards

1
Q

Protozoa are a diverse group of microscopic, unicellular organisms that have unique characteristics and play various roles in different ecosystems. The term “protozoa” comes from the Greek words “protos,” meaning “first,” and “zoon,” meaning “animal,” highlighting their position as some of the earliest forms of animal-like life

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2
Q

general features of protozoa

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Single “Cell-like Unit”:

  • Protozoa are single-celled organisms, but despite their unicellular nature, they function as complete units, performing all necessary life processes within one cell. This means they can move, feed, reproduce, and sense their environment just like multicellular organisms.

Specialized Organelles:

  • Instead of organs or tissues, protozoa have specialized organelles. These organelles perform functions similar to the organs in multicellular organisms. For example, they have structures for movement (like cilia or flagella), digestion (like food vacuoles), and excretion.

Diversity and Species Count:

  • Over 64,000 species of protozoa have been identified, with about half of these known only from fossils. While most protozoa are non-pathogenic and harmless, a few species can cause diseases in humans and other animals.

Ecological Range:

  • Protozoa are incredibly diverse in their ecological niches. They can be found in almost every environment, from aquatic habitats (both freshwater and marine) to terrestrial ones. However, some species have very specific environmental requirements and can only thrive under certain conditions.

Living Modes:

  • Protozoa can be free-living, symbiotic, or parasitic:

Free-living: These protozoa live independently in their environments, such as in water bodies or soil.

Symbiotic: These protozoa live in close association with other organisms, which can be either mutualistic (beneficial to both parties) or commensal (beneficial to the protozoan without harming the host).

Parasitic: These protozoa live at the expense of their host, causing diseases. For example, Plasmodium species cause malaria in humans.

Colonial and Non-Colonial Forms:

  • Some protozoa can form colonies with multicellular stages, although they also have non-colonial forms during their life cycle. This ability to switch between colonial and solitary forms allows them to adapt to different environmental conditions.

Lack of Cell Wall:

  • Unlike plants and fungi, protozoa do not have a rigid cell wall. Their shape is instead determined by the materials beneath their plasma membrane, such as the cytoskeleton. This allows for greater flexibility and mobility.

Motility:

  • At least one stage in the life cycle of protozoa is motile. They use various structures for movement:

Flagella: Long, whip-like structures that propel the organism through its environment.

Cilia: Short, hair-like structures that beat in coordinated waves for movement.

Pseudopodia: Temporary, foot-like extensions of the cell membrane and cytoplasm that enable movement and feeding.

Feeding:

  • Most protozoa ingest their food. They are heterotrophic, meaning they obtain their nutrients by consuming other organisms or organic matter. They can engulf food particles through a process called phagocytosis, forming food vacuoles where digestion takes place.
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3
Q

Summary

Protozoa are highly diverse, single-celled organisms that perform all life functions within a single cell. They possess specialized organelles instead of organs or tissues, and they can exist in a variety of ecological niches. Protozoa can be free-living, symbiotic, or parasitic, and they exhibit different modes of mobility and feeding. Their lack of a cell wall and diverse structural forms allow them to adapt to various environments. Despite their simplicity, protozoa play significant roles in ecological systems and can impact human health through parasitic species.

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4
Q

Protozoa ingest food particles through a process called ____.

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phagocytosis

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5
Q

describe the steps how protozoa handle and digest food:

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Formation of Phagosomes (Food Vacuoles):

  • When a protozoan engulfs a food particle, the plasma membrane surrounds the particle, forming a pocket that pinches off into the cell to become an enclosed food particle, known as a phagosome or food vacuole.

Digestion:

  • Lysosomes, which contain digestive enzymes, fuse with the phagosome. These enzymes are then released into the phagosome, breaking down the food particle into simpler, absorbable molecules.

Absorption and Reduction of Phagosomes:

  • As the food is digested and absorbed into the cytoplasm, the size of the phagosome reduces. The remnants that cannot be digested are eventually expelled from the cell.
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6
Q

Protozoa exhibit various nutritional modes which are?

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Autotrophic Nutrition:

Some protozoa, like Euglena, contain chloroplasts and can perform photosynthesis, producing their own food using sunlight, carbon dioxide, and water.

Heterotrophic Nutrition:

  • Most protozoa are heterotrophic, meaning they obtain their nutrients by ingesting other organisms or organic matter. This includes predation on other microorganisms or scavenging dead organic material.

Saprozoic Nutrition:

Some protozoa absorb dissolved organic substances directly from their environment, a mode of nutrition known as saprozoic nutrition.

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7
Q

Protozoa have specialized structures for locomotion, which also serve as a basis for their classification
List them

A

Cilia:

Short, hair-like structures that beat rhythmically to propel the organism through its environment. An example is Paramecium.

Pseudopodia:

Temporary, foot-like extensions of the cell membrane and cytoplasm that enable movement and capturing food. Amoeba is a typical example.

Flagella:

Long, whip-like structures that rotate or undulate to move the organism. Trypanosoma and Euglena use flagella for movement.

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8
Q

Classification by Locomotion

Group protozoa based on their mode of locomotion:

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Ciliates: Move using cilia (e.g., Paramecium).

Amoeboids: Move using pseudopodia (e.g., Amoeba).

Flagellates: Move using flagella (e.g., Euglena).

Sporozoans: Typically non-motile in their mature form and often parasitic (e.g., Plasmodium).

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9
Q

Protozoa can reproduce both asexually and sexually, utilizing various methods
List all the methods under both

A

:

Asexual Reproduction:

  • Fission: The parent cell divides into two or more daughter cells. This can be binary fission (one cell splits into two) or multiple fission (one cell divides into multiple offspring).
  • Budding: A new organism develops from an outgrowth or bud due to cell division at one particular site. The bud remains attached as it grows, separating only when it is fully mature.
  • Cysts: In unfavorable conditions, protozoa can form cysts, which are dormant, tough, and resistant structures that can survive until conditions improve.

Sexual Reproduction:

  • Conjugation: Two protozoa come together and exchange genetic material through a temporary cytoplasmic bridge, enhancing genetic diversity. This process is seen in ciliates like Paramecium.
  • Syngamy: Fusion of gametes, where two specialized sex cells (gametes) combine to form a zygote. This process is common in sporozoans.
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10
Q

Summary

Protozoa are highly versatile unicellular organisms with diverse nutritional and locomotion strategies. They can digest food particles through the formation of phagosomes and subsequent fusion with lysosomes. Protozoa can be autotrophic, heterotrophic, or saprozoic in their nutritional habits. Their movement structures include cilia, pseudopodia, and flagella, which also help classify them. Reproduction in protozoa can be asexual, through fission, budding, or cyst formation, or sexual, through conjugation or syngamy. These characteristics enable protozoa to thrive in a wide range of environments and contribute significantly to ecological processes.

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11
Q

Morphological Traits

Protozoa are often classified by their morphological features, including the structures they use for locomotion and other physical characteristics.
Classify them

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Flagella: Long, whip-like structures that propel the protozoan through its environment. Examples include Euglena and Trypanosoma.

Cilia: Short, hair-like structures that cover the cell surface and beat rhythmically for movement. Examples include Paramecium and Balantidium.

Pseudopodia: Temporary, foot-like extensions of the cell membrane and cytoplasm used for movement and capturing food. Examples include Amoeba and Entamoeba.

Shells (Tests): Some protozoa, such as foraminifera and radiolarians, have shells or tests made of calcium carbonate or silica. These shells can provide protection and aid in buoyancy

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12
Q

Characteristic Organelles

Certain organelles are distinctive to specific groups of protozoa and play crucial roles in their classification.

What are they?

A

Apical Complex: A specialized structure used for penetrating host cells, characteristic of the phylum Apicomplexa (e.g., Plasmodium, Toxoplasma).

Kinetoplast: A mass of mitochondrial DNA found near the base of the flagellum, characteristic of kinetoplastids (e.g., Trypanosoma, Leishmania).

Presence/Absence of Mitochondria: Some protozoa have mitochondria (e.g., most ciliates, flagellates), while others lack them, especially those adapted to anaerobic conditions (e.g., Giardia, Trichomonas).

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13
Q

Classify the protozoa based on Trophism

Protozoa can be classified based on their mode of nutrition, which includes both autotrophic and heterotrophic strategies.

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Heterotrophic: Protozoa that obtain their nutrients by consuming other organisms or organic matter. This includes most protozoa that ingest bacteria, algae, or smaller protozoa.

Autotrophic: Protozoa that produce their own food through photosynthesis. Examples include Euglena and other photosynthetic flagellates.

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14
Q

Subkingdom Protozoa includes a variety of single-celled eukaryotic organisms that are classified based on their mode of locomotion, morphology, and other characteristics. Within this subkingdom, one of the major phyla is Phylum Sarcomastigophora, which includes protozoa that move using flagella or pseudopodia.

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15
Q

Phylum Sarcomastigophora is characterized by protozoa that use either ___ or ____for movement.

A

flagella or pseudopodia

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16
Q

What’s the sub phylum of Phylum Sarcomastigophora

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Subphylum Sarcodina

Subphylum Sarcodina consists of protozoa that primarily move by extending pseudopodia, which are temporary projections of the cell membrane and cytoplasm.

Superclass Rhizopodea

  • Superclass Rhizopodea includes protozoa that utilize pseudopodia for locomotion and feeding, but do not possess axopods (long, thin pseudopodia supported by microtubules).

Order Amoebida

  • Order Amoebida is characterized by amoeboid protozoa that lack a protective shell, making them “naked.”
  • Family Vahlkampfiidae

Protozoa in Family Vahlkampfiidae undergo nuclear division by a process called promitosis, and they may possess flagella.

Genus Naegleria: An example of this family, Naegleria includes species that can alternate between amoeboid and flagellate forms, such as Naegleria fowleri, known for causing a rare and often fatal brain infection.

Family Hartmannellidae

  • Family Hartmannellidae comprises protozoa whose nuclear division is not promitotic (nuclear envelope remains intact during division), and they do not have flagella.

Genus Acanthamoeba: These protozoa are found in soil and water, and some species, like Acanthamoeba castellanii, can cause infections in humans, particularly in the eyes and central nervous system.

Family Endamoebidae
- Protozoa in Family Endamoebidae lack flagella and are typically found in the digestive tracts of their hosts.

Genus Entamoeba: This genus includes species like Entamoeba histolytica, which causes amoebic dysentery and liver abscesses in humans. They are characterized by their ability to form cysts that are transmitted through contaminated food and water.

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17
Q

Summary

The classification of protozoa within Subkingdom Protozoa and Phylum Sarcomastigophora is detailed based on their locomotion mechanisms and other defining traits:

Phylum Sarcomastigophora: Protozoa with flagella or pseudopodia.
Subphylum Sarcodina: Locomotion by pseudopodia.
Superclass Rhizopodea: Pseudopodia, not axopods.
Order Amoebida: Naked, no shell.
Family Vahlkampfiidae: Nuclear division by promitosis, flagella may be present.
Genus Naegleria
Family Hartmannellidae: Nuclear division not promitotic, flagellum absent.
Genus Acanthamoeba
Family Endamoebidae: No flagella, typically in the digestive tract.
Genus Entamoeba

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18
Q

Phylum Ciliophora encompasses protozoa that possess cilia or ciliary organelles at some stage in their life cycle. These cilia are used for movement and feeding. Within this phylum, various classes, subclasses, families, and genera are distinguished based on specific morphological and functional characteristics.

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19
Q

Break down phylum Phylum Ciliophora

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  • Subphylum Rhabdophora: Features a ciliary crown around the cytostome.
    • Class Litostomatea: Has monokinetids with tangential transverse ribbon cilia.
      • Subclass Trichostomatia: Lacks oral toxicysts.
        • Family Balantidiidae: Long cytostome and oral cavity, body cilia holotrichous.
          • Genus Balantidium: Includes Balantidium coli
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20
Q

Phylum Ciliophora

Phylum Ciliophora: Protozoa with cilia or ciliary organelles at some stage.

Subphylum Rhabdophora

  • Subphylum Rhabdophora includes ciliates with a characteristic ciliary crown around the cytostome (the cell mouth).

Class Litostomatea

  • Class Litostomatea is distinguished by monokinetids (a type of ciliary unit) with tangential transverse ribbon cilia present in only two orders.

Subclass Trichostomatia

  • Subclass Trichostomatia: Protozoa in this subclass lack oral toxicysts (structures used to capture and paralyze prey).

Family Balantidiidae

  • Family Balantidiidae: Characterized by having a long cytostome and oral cavity, with body cilia arranged in a holotrichous pattern (uniformly covering the body).

Genus Balantidium: This genus includes Balantidium coli, a ciliate that can cause opportunistic infections in humans, typically in the intestinal tract.

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21
Q

Medically Important Protozoa

Certain protozoa are of medical significance due to their ability to cause diseases in humans. They are categorized based on the site of infection: intestinal, vaginal, blood, tissue, and free-living amoebae.

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22
Q

What are the intestinal causes ones?

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Intestinal Protozoa

Entamoeba histolytica: Causes amoebiasis, characterized by diarrhea, dysentery, and liver abscesses. It is transmitted via contaminated food and water.

Giardia intestinalis (G. lamblia): Causes giardiasis, which presents with gastrointestinal symptoms such as diarrhea and abdominal cramps. It is also spread through contaminated water.

Balantidium coli: A ciliate causing opportunistic infections, primarily in the intestines. It can lead to balantidiasis, with symptoms similar to amoebiasis.

Isospora belli: Causes isosporiasis, an intestinal infection leading to diarrhea and weight loss, particularly in immunocompromised individuals.

Cryptosporidium: Responsible for cryptosporidiosis, marked by watery diarrhea, often severe in immunocompromised patients

23
Q

What are The Vaginal Protozoa causes

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Trichomonas vaginalis: Causes trichomoniasis, a sexually transmitted infection resulting in vaginal discharge and irritation.

24
Q

The causes of Blood Protozoa

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Plasmodium: Causes malaria, transmitted by Anopheles mosquitoes. Symptoms include fever, chills, and anemia.

Leishmania: Causes leishmaniasis (Kala Azar), transmitted by sandflies. It affects the skin, mucous membranes, and internal organs.

Trypanosoma: Causes sleeping sickness (African trypanosomiasis), transmitted by tsetse flies. It leads to fever, headaches, and neurological symptoms.

25
Q

What are the causes of tissue and free living protozoa?

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Tissue Protozoa

Toxoplasma gondii: Causes toxoplasmosis, which can affect the brain, eyes, and other organs. It is particularly dangerous for immunocompromised individuals and pregnant women.

Free-Living Amoebae

Acanthamoeba: Causes meningoencephalitis and keratitis, infections of the brain and eyes, respectively.

Naegleria: Causes primary amebic meningoencephalitis (PAM), a rare but usually fatal brain infection

26
Q

Medically important protozoa are categorized by infection site:

Intestinal: Entamoeba histolytica, Giardia intestinalis, Balantidium coli, Isospora belli, Cryptosporidium.

Vaginal: Trichomonas vaginalis.

Blood: Plasmodium, Leishmania, Trypanosoma.

Tissue: Toxoplasma gondii.

Free-Living Amoebae: Acanthamoeba, Naegleria

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27
Q

What’s Entamoeba histolytica

A

Entamoeba histolytica is a protozoan parasite responsible for amoebiasis, a disease that primarily affects the gastrointestinal tract but can also impact other organs such as the liver

28
Q

What’s Entamoeba histolytica

A

Entamoeba histolytica is a protozoan parasite responsible for amoebiasis, a disease that primarily affects the gastrointestinal tract but can also impact other organs such as the liver

29
Q

Gastrointestinal Pathology

Tell me all you can about Amoebic Trophozoites and Colitis

It’s Invasion of the Colon: & Spectrum of Colitis

A

Amoebic Trophozoites and Colitis

Invasion of the Colon: Amoebic trophozoites, the active form of E. histolytica, invade the colon’s mucosal lining, leading to colitis. Colitis is an inflammation of the inner lining of the colon.

Spectrum of Colitis: The severity of colitis caused by E. histolytica can vary widely:

Mucosal Thickening: This is a less severe form where the mucosa becomes thickened.

Cyst Formation: Multiple cysts can form within the colon.

Diffuse Inflammation and Edema: More severe cases involve widespread inflammation and swelling of the colon.

Necrosis and Perforation: In the most severe cases, the colon wall can undergo necrosis (tissue death) and perforation (holes or tears).

30
Q

Tell me all you can about Flask-Shaped Cysts

It’s Submucosal Invasion

A

Flask-Shaped Cysts

Submucosal Invasion: The trophozoites invade through the mucosal layer to the submucosa, creating flask-shaped cysts. These cysts are characteristic of amoebiasis and result from the trophozoites burrowing into the tissue.

31
Q

Whats the Immune Response and Tissue Damage of E. histolytica

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Immune Response and Tissue Damage

Neutrophils and Macrophages: The body’s immune response includes the recruitment of neutrophils and macrophages to the site of invasion. These white blood cells attempt to fight off the infection.

Lysis of Neutrophils: E. histolytica trophozoites can lyse (break down) neutrophils, releasing their contents and causing additional tissue damage.

Diarrhea Induction: The lysis of neutrophils and the ensuing inflammation contribute to the development of diarrhea, a common symptom of amoebiasis.

Inflammation vs. Innate Immunity: While inflammation significantly contributes to tissue damage, the body’s innate immunity plays a crucial role in combating the disease.

32
Q

Hepatic Pathology

Liver Involvement, hepatic invasion

Of E. histolytica

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Hepatic Pathology

Liver Involvement

Hepatic Invasion: Trophozoites that invade the colonic mucosa can enter the hepatic (liver) circulation and travel to the liver.

Liver Abscesses: In the liver, the trophozoites form well-circumscribed abscesses. These abscesses contain liquefied cells surrounded by inflammatory cells and active trophozoites.

33
Q

Summary

Entamoeba histolytica causes amoebiasis by invading the colon and, in severe cases, spreading to the liver.

Gastrointestinal Pathology:

The infection ranges from mild mucosal thickening to severe necrosis and perforation of the colonic wall.

Trophozoites create characteristic flask-shaped cysts in the submucosa.

The immune response involves neutrophils and macrophages, but E. histolytica can lyse neutrophils, causing further tissue damage and contributing to diarrhea.

Inflammation causes significant tissue damage, though innate immunity is crucial in fighting the infection.

Hepatic Pathology:

Trophozoites can reach the liver via the hepatic circulation, leading to the formation of liver abscesses containing liquefied cells, inflammatory cells, and trophozoites.

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34
Q

The Protozoa: Tissue Dwelling Amoebae examples

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Naegleria fowleri
Acanthamoeba keratitis

35
Q

Naegleria fowleri is what type of protozoa?

A

Naegleria fowleri is an ameboflagellate, meaning it is capable of existing in both amoeboid and flagellated forms

It is a free-living organism, which means it can survive independently in the environment without requiring a host.

Only the amoeboid form is found in human tissues, where it causes infection.

36
Q

Whats the life cycle of Naegleria fowleri

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Life Cycle

Entry Point: Naegleria fowleri typically enters the human body through the nasal mucosa, often during activities such as swimming in warm, fresh water.

Path of Infection: After entry, the amoeba travels along the olfactory nerve, reaching the brain through the cribriform plate (a part of the skull located between the nasal cavity and the brain).

Invariably Fatal: The infection caused by N. fowleri is almost always fatal.

Non-Contagious: Infections do not spread from person to person.

37
Q

What are the symptoms of Naegleria fowleri

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Symptoms

  • Rapid Progression: The symptoms of Naegleria fowleri infection are dramatic and progress rapidly.
  • Initial Symptoms: Within 1 to 2 days, infected individuals may experience headache, fever, nausea, and vomiting.
  • Severe Neurological Symptoms: The infection quickly escalates to meningoencephalitis (inflammation of the brain and its surrounding membranes), irrational behavior, coma, and eventually death.
  • Time Frame: Death usually occurs within 9 days of exposure to the amoeba.
38
Q

Summary

Naegleria fowleri is a highly dangerous, free-living ameboflagellate that primarily affects the brain. Its classification as an ameboflagellate reflects its ability to alternate between amoeboid and flagellated forms, though only the amoeboid form is found in tissues.

Life Cycle:

The amoeba enters through the nasal mucosa, often during water-related activities.
It travels along the olfactory nerve to the brain, leading to fatal infections.
The infection is non-contagious.

Symptoms:

Symptoms appear rapidly, starting with headache, fever, nausea, and vomiting.
The condition quickly progresses to meningoencephalitis, irrational behavior, coma, and death within 9 days of exposure.

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39
Q

The Protozoa: Tissue Dwelling Amoebae - Acanthamoeba spp (culbertsoni)
- Acanthamoeba spp., including Acanthamoeba culbertsoni, are free-living amoebae known to cause serious infections in humans.

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40
Q

Whats the Life Cycle of Acanthamoeba

A

Life Cycle

Free-Living Nature:

Acanthamoeba species are free-living amoebae, meaning they do not need a host to survive in the environment.

Entry Points:

  • Skin Wounds or Lesions: The amoeba can enter the body through wounds or lesions on the skin. Once inside, it reaches the brain via the bloodstream (hematogenously).
  • Eyes: More commonly, Acanthamoeba enters the eyes through contaminated or homemade cleaning solutions, especially in the case of contact lens users.
41
Q

Whats are the symptoms of Acanthamoeba

A

Symptoms

Onset and Presentation:

  • Slow Onset: Symptoms of Acanthamoeba infection develop slowly, often taking 10 or more days to appear.
  • Brain Lesions: The infection can present as chronic, granulomatous lesions in the brain. Granulomas are small areas of inflammation caused by the immune system’s attempt to wall off substances it perceives as foreign but is unable to eliminate.
  • Eye Lesions: When Acanthamoeba infects the eye, the symptoms can resemble those of a herpes virus infection. This can include pain, redness, blurred vision, and tearing.
42
Q

What’s Acanthamoeba keratitis & it’s symptoms

A

Acanthamoeba Keratitis:

Contact Lens Users: Acanthamoeba keratitis is a serious eye infection associated with the use of extended-wear contact lenses.

Symptoms: The symptoms can include severe pain, redness, blurred vision, sensitivity to light, and excessive tearing. The infection can lead to corneal ulcers and potentially severe vision impairment or blindness if not treated promptly

43
Q

Summary

Acanthamoeba spp. are free-living amoebae capable of causing severe infections, particularly in the brain and eyes.

Life Cycle:

The amoeba enters the body through skin wounds or lesions, reaching the brain via the bloodstream.
It is commonly associated with eye infections, particularly from contaminated cleaning solutions for contact lenses.

Symptoms:

Symptoms have a slow onset, often taking 10 or more days to manifest.
In the brain, it presents as chronic, granulomatous lesions.

In the eyes, the infection can mimic herpes virus infection symptoms.
Acanthamoeba keratitis is notably associated with extended-wear contact lens users and can cause severe ocular damage.

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44
Q

What’s Balantidium coli

A

Balantidium coli

Introduction

Balantidium coli is the only ciliate parasite of humans and the largest intestinal protozoan causing gastroenteritis in humans. It has two stages in its life cycle: the trophozoite stage and the cyst stage.

45
Q

What are the characteristics of Balantidium coli

A

Characteristics

Pathogenic Intestinal Ciliate:
- Balantidium coli is unique as it is the only ciliate known to be pathogenic to humans.

Size:

  • The trophozoite stage is the largest among parasitic protozoans, measuring between 30-120 microns in length and 25-125 microns in width.

The cyst stage, which is the infectious form, typically measures 50-70 microns in diameter.

46
Q

What’s the life cycle of Balantidium coli

A

Life Cycle

  • Cyst Ingestion: The life cycle of Balantidium coli begins when cysts are ingested through fecally contaminated food or water.
  • Excystation: Once ingested, the cysts excyst (release trophozoites) in the small intestine.
  • Trophozoite Migration: The trophozoites then migrate to the large intestine, where they can cause infection and symptoms of gastroenteritis.
47
Q

Summary

Balantidium coli is a significant parasitic protozoan due to its unique characteristics and life cycle.

Characteristics:

It is the only pathogenic intestinal ciliate in humans.
It is the largest intestinal protozoan, with trophozoites measuring 30-120 x 25-125 microns and cysts averaging 50-70 microns in diameter.
Life Cycle:

The infectious cysts are ingested via fecal contamination.
The cysts excyst in the small intestine, releasing trophozoites.
The trophozoites then migrate to the large intestine, where they cause gastroenteritis.

Understanding the life cycle and characteristics of Balantidium coli is crucial for diagnosing and managing infections caused by this protozoan.

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48
Q

The Protozoa: Class Ciliophora - The Ciliates

Whats the Pathology & Symptoms of Balantidium coli

A

Pathology & Symptoms

Asymptomatic Infections:
- Many infections with Balantidium coli are asymptomatic. In these cases, the organism primarily feeds on bacteria at the surface of the mucosa without causing significant harm.

Severe Infections:
- In more severe cases, Balantidium coli uses the enzyme hyaluronidase to penetrate the submucosa of the large intestine, leading to ulcer formation.

Symptoms: Severe infections can result in:

Dysentery: Characterized by severe diarrhea with blood and mucus in the stool.

Abdominal Pain: Discomfort or pain in the abdomen.

Nausea & Vomiting: Feelings of sickness with an urge to vomit.

Fever: Elevated body temperature.

Headache: Pain in the head.

49
Q

Whats the morphology of Balantidium coli

A

Morphology

Shape and Size: Balantidium coli is large and oval-shaped.

Nuclei: It has two nuclei:

Macronucleus: A large, kidney-shaped nucleus responsible for vegetative functions.

Micronucleus: A small nucleus involved in reproductive functions, though it is not often seen.

Cilia: The body surface is covered by longitudinal rows of cilia, which are hair-like structures that aid in movement.

Cytostome: A cell mouth, used for ingesting food particles, is present.

50
Q

Animal Reservoirs

Primary Reservoirs: The primary animal reservoirs for Balantidium coli include pigs and monkeys. These animals can harbor the parasite and facilitate its transmission to humans.

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51
Q

Summary

Balantidium coli is a significant ciliate protozoan parasite due to its unique pathology, morphology, and transmission dynamics.

Pathology & Symptoms:

Asymptomatic Infections: Often, infections are asymptomatic with the organism feeding on bacteria at the mucosal surface.

Severe Infections: In severe cases, the parasite uses hyaluronidase to penetrate the submucosa, leading to ulcer formation and symptoms such as dysentery, abdominal pain, nausea and vomiting, fever, and headache.

Morphology:

Large and Oval-Shaped: Characterized by its large size and oval shape.
Two Nuclei: Possesses a large macronucleus and a small micronucleus.
Cilia and Cytostome: Body surface covered by cilia and a cytostome for ingesting food particles.

Animal Reservoirs:

Primary Hosts: Pigs and monkeys are the main animal reservoirs, playing a crucial role in the transmission of Balantidium coli to humans.

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