Classification of proteins Flashcards

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1
Q

How do we classify proteins ?

A
  • Based on structure
  • Based on composition
  • Based on functions
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2
Q

Classification based on structure

A
  • Fibrous proteins
  • Globular proteins
  • Intermediate proteins
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3
Q

Classification based on composition

A
  • Simple Proteins
  • Conjugated proteins
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4
Q

Classification based on functions

A
  • Structural
  • Enzymes
  • Hormones
  • Respiratory pigments
  • Transport proteins
  • Contractile proteins
  • Storage proteins
  • Immunoglobulins
  • Toxins
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5
Q

Fibrous Proteins

A
  • Linear
  • Tough & strong
  • Long parallel polypeptide chains cross linked at regular intervals
  • Perform structural functions in the cells
  • Usually do not have a (complex) tertiary structure
  • Insoluble in water
  • Most important structure: secondary structure
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6
Q

Examples of fibrous proteins

A
  • Collagen
  • Elastin
  • Myosin
  • Keratin
  • Silk
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7
Q

Globular proteins

A
  • Spherical/globular shape
  • Polypeptide chain tightly folded into spherical shapes
  • Physically softer
  • Most proteins in cells are globular proteins
  • Function: form enzymes, antibodies and some hormones
  • Readily soluble in water
  • Most important structure: Tertiary Structure
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8
Q

Examples of globular proteins

A
  • insulin
  • hemoglobin
  • albumin
  • DNA polymerase and RNA polymerase
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9
Q

Intermediate proteins

A
  • Intermediate shape more or less linear
  • Soluble in water
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10
Q

Example of intermediate protein

A

Blood clotting proteins

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11
Q

Simple proteins

A
  • Composed of only amino acids, relatively simple structure
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12
Q

Examples of simple proteins

A
  • Myosin
  • Collagen
  • Keratin
  • Insulin
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13
Q

Conjugated proteins

A
  • Complex, contains one or more non-amino acid component called prosthetic groups, essential for biological function.
  • Usually globular and soluble in water
  • Most enzymes are conjugated proteins
  • Further classification based on the nature of the prosthetic groups
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