Classic/Relevant Treatments II

Question 1

Cyclophosphamide-induced hemorrhagic cystitis

Answer 1

Mesna

Question 2

Depression

Answer 2

SSRI’s (first line)

Question 3

Diabetes insipidus

Answer 3

Desmopressin (central)

Hydrochlorothiazide, indomethacin, imiloride (nephrogenic)

Question 4

DM type I

Answer 4

Dietary intervention (low carb) + insulin replacement

Question 5

DM type II

Answer 5

Dietary intervention, oral hypoglycemics, and insulin (if refractory)

Question 6

Diabetic ketoacidosis

Answer 6

Fluids, insulin, K+

Question 7

Enterococci

Answer 7

Vancomycin, aminopenicillins/cephalosporins

Question 8

Erectile dysfunction

Answer 8

Sildenafil, tadalafil, vardenafil

Question 9

ER+ Breast cancer

Answer 9

Tamoxifen

Question 10

Ethylene glycol/methanol intoxication

Answer 10

Fomepizole (alcohol dehydrogenase inhibitor)

Question 11

Haemophilus influenzae (B)

Answer 11

Rifampin (prophylaxis)

Question 12

GAD

Answer 12

SSRI’s, SNRI’s (first line);

Buspirone (second line)

Question 13

Granulomatosis with polyangiitis (Wegener)

Answer 13

Cyclophosphamide, corticosteroids)

Question 14

Heparin reversal

Answer 14

Protamine sulfate

Question 15

HER2/neu + breast cancer

Answer 15

Trastuzumab

Question 16

Hyperaldosteronism

Answer 16

Spironolactone

Question 17

Hypercholesterolemia

Answer 17

Statin (first line)

Question 18

Hypertriglyceridemia

Answer 18

Fibrate

Question 19

Immetiate anticoagulation

Answer 19

Heparin

Question 20

Infertility

Answer 20

Leuprolide, GnRH (pulsatile), clomiphene

Question 21

Influenza

Answer 21

Oseltamivir, zanamivir

Question 22

Kawasaki disease

Answer 22

Aspirin, IvIG

Question 23

Legionella pneumophila

Answer 23

Macrolides

Question 24

Long-term anticoagulation

Answer 24

Warfarin, dabigatran, rivaroxiban and apixaban

Question 25

Malaria

Answer 25

Chloroquine, mefloquin, atorvoquone/proguanil (for blood schizont) Primaquin (for liver hypnozoite)

Question 26

Malignant hyperthermia

Answer 26

Dantrolene

Question 27

Abortion

Answer 27

Mifepristone

Question 28

Migraine

Answer 28

``` Abortive therapies (sumatriptan, NSAIDs); Prophylaxis (propanolol, topiramate, CCBs, amitriptyline) ```

Question 29

Multiple sclerosis

Answer 29

Disease-modifying therapies (Beta interferon, natalizumab) | For acute flares, IV steroids

Question 30

Mycobacterium tuberculosis

Answer 30

RIPE (rifampin, isoniazid, pyrazinamide, ethambutol)

Question 31

Neisseria gonorrhea

Answer 31

Ceftriaxone (add doxycycline for concurrent C. trachomatis)

Question 32

Neisseria meningitidis

Answer 32

Penicillin/ceftriaxone, rifampin (prophylaxis)