Classic/Relevant Treatments

Question 1

Ethylene glycol/methanol intoxication

Answer 1

Fomepizole (alcohol dehydrogenase inhibitor)

Question 2

Chronic Hepatitis B or C

Answer 2

INF alpha (HBV and HCV); ribavirin, simeprevir, sofosbuvir (HCV)

Question 3

Streptococcus bovis

Answer 3

Penicillin prophylaxis; evaluation for colon cancer if linked to endocarditis

Question 4

Clostridium botulinum

Answer 4

Human botulinum immunoglobulin

Question 5

Clostridium tetani

Answer 5

Antitoxin and wound debridement

Question 6

Clostridium difficile

Answer 6

Oral metronidazole; if refractory, oral vancomycin. Refractory case: repeat regimen or fecal microbiota transplant

Question 7

Haemophilus influenzae (B)

Answer 7

Amoxicillin +/- clavulanate (mucosal infection), ceftriaxone (meningitis), rifampin (prophylaxis)

Question 8

Neisseria gonorrhoeae

Answer 8

Ceftriaxone (add azithromycin or doxycycline to cover likely concurrent C trachomatis

Question 9

Neisseria meningitidis

Answer 9

Penicillin/ceftriaxone, rifampin/ciprofloxacin/ceftriaxone (prophylaxis)

Question 10

Legionella pneumophila

Answer 10

Macrolides (eg azithromycin or fluoroquinolones)

Question 11

Pseudomonas aeruginosa

Answer 11

Piperacillin-tazobactam, cephalosporins, monobactams, fluoroquinolones, carbapenems

Question 12

Treponema pallidum

Answer 12

Penicillin G

Question 13

Chlamydia trachomatis

Answer 13

Azithromycin or doxycycline (+ ceftriaxone for gonorrhea conifection), oral erythromycin to treat chlamydial conjunctivitis in infants