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Rapid Review > Classic Pt Present > Flashcards

Classic Pt Present Flashcards

1
Q

Abdominal pain, ascites, hepatomegaly

A

Budd Chiari Syndrome (posthepatic venous thrombosis)

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2
Q

Achilles Tendon xanthoma

A

Familial hypercholesterolemia ( low LDL receptor signaling)

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3
Q

Adrenal Hemorrhage, Hypotension, DIC

A

Waterhouse-Friderichsen Syndrome (Meningococcemia)

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4
Q

Arachnodactyly, lens discolation, aortic dissection, hyperflexible joints

A

Marfan’s Syndrome (Fibrillin defect)

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5
Q

Athlete w/ polycythemia

A

Secondary to erythropoietin injection

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6
Q

Back pain, fever, night sweats, weight loss

A

Pott’s Disease (TB in vertebrae)

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7
Q

B/L Hilar adenopathy, uveitis

A

Sarcoidosis (Noncaseating granuloma)

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8
Q

Blue Sclera

A

Osteogenesis Imperfecta (Type 1 collagen defect)

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9
Q

Bluish line on gingiva

A

Burton’s line (Lead poisoning)

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10
Q

Bone pain, bone enlargement, arthritis

A

Paget’s Disease (inc. osteoblast/clast activity)

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11
Q

Bounding pulses, diastolic heart murmur, head bobbing

A

Aortic Regurgitation

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12
Q

Butterfuly (malar) rash and Raynaud’s phenom in young female

A

SLE

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13
Q

Cafe-au-alit spots, Lisch nodules (iris hamartoma)

A

Neurofibromatosis type I (+ pheochromocytoma, optic glioma)

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14
Q

Calf pseudohypertophy

A

Muscular Dystrophy (MC Duchenne’s muscular dystrophy); x-linked recessive deletion of Dystrophin gene

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15
Q

“Cherry-red spot” on macula

A

Tay-Sach’s (Ganglioside accumulations) or Niemann-Pick (sphingomyelin accumulation), central retinal artery occlusion

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16
Q

Chest pain on exertion

A

Angina (Stable, unstable)

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17
Q

Chest pain, pericardial effusion/friction rub, persistent fever FOLLOWING MI

A

Dressler’s Syndrome (autoimmune mediated post MI fibrinous pericarditis, 1-12 wks post acut MI)

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18
Q

Cafe-au-lait spots, polyostotic fibrous dysplasia, precocious puberty, multiple endocrine abnorms

A

McCune-Alrbright Syndrome (mosaic G-protein signaling mutation)

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19
Q

Child uses arms to stand up from squatting

A

Gower’s Sign (Duchenne’s Muscular Dystrophy)

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20
Q

Child w/ fever later develops red rash on face that spreads to body

A

“Slapped cheeks” (erythema infectiosum/fifth disease; parvovirus B19)

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21
Q

Chorea, Dementia, Caudate degeneration

A

Hungtington’s Disease (auto-dominant CAG repeat expansion)

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22
Q

Chronic exercise intolerance with myalgia, fatigue, painful cramps, myoglobinuria

A

McArdle’s Disease (muscle glycogen phosphorylase deficiency)

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23
Q

Cold Intolerance

A

Hyothyrodism

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24
Q

Conjugate lateral gaze palsy, horizontal diplopia

A

Internuclear opthalmoplegia (damage to MLF; bilateral [multiple sclerosis], Unilateral [Stoke])

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25
Q

Continuous “machinery” heart murmur

A

Patent Ductus Arteriosus (close w/ Indomethacin; open or maintain w/ Misoprostol)

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26
Q

Cutaneous/dermal edema due to connective tissue deposition

A

Myxedema (caused by hypothyroidism, Grave’s disease [pretibial])

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27
Q

Dark purple skin/mouth nodules

A

Kaposi’s Sarcoma (AIDS pts [MSM]: associated w/ HHV-8)

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28
Q

Deep, labored breathing/hyperventilation

A

Kussmaul breathing (diabetic ketoacidosis)

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29
Q

Dermatitis, dementia, diarrhea

A

Pellagra (niacin [vit B3] deficiency)

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30
Q

Dilated cardiomyopathy, edema, alcoholism or malnutrition

A

Wet beriberi (thiamine [vit B1] deficiency)

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31
Q

Dog or cat bite resulting in infection

A

Pasteurella multocida (cellulitis at inoculation site)

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32
Q

Dry eyes, dry mouth, arthritis

A

Sjogren’s Syndrome (autoimmune destruction of exocrine glands)

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33
Q

Dysphagia (esophageal webs), glossitis, iron deficiency anemia

A

Plummer-Vinson syndrome (may progress to esophageal sq cell carcinoma)

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34
Q

Elastic skin, hypermobility of joints

A

Ehlers-Danlos Syndrome (type III collagen defect)

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35
Q

Enlarged, hard left supraclavicular node

A

Virchow’s nodule (Abdominal metastasis)

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36
Q

Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells

A

Sezary Syndrome (cutaneous T-cell lymphoma or Mycosis Fungoides

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37
Q

Facial muscle spasm upon tapping

A

Chvostek’s sign (hypocalcemia)

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38
Q

Fat, female, forty, and fertile

A

Cholelithiasis (gallstones)

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39
Q

Fever, chills, headache, mylagia following antibiotic treatment for syphilis

A

Jarisch-Herxheimer reaction (rapid lysis of spirochetes results in toxin release)

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40
Q

Fever, cough, conjunctivits, coryza, diffuse rash

A

Measles (Morbillivirus)

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41
Q

Fever, night sweats, weight loss

A

B symptoms (staging) of lymphoma

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42
Q

Fibrous plaques in soft tissue of penis

A

Peyronie’s disease (CT disorder)

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43
Q

Gout, mental retardation, self-mutilating behavior in a boy

A

Lesch-Nyhan syndrome (HGPRT deficiency, X-linked recessive)

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44
Q

Green-yellow rings around peripheral cornea

A

Kayser-Fleischer rings (copper build up from Wilson’s Disease)

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45
Q

Hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands

A

Peutz-Jeghers syndrome (inherited, benign polyposis can cause bowel obstruction; increased cancer risk, mainly GI)

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46
Q

Hepatosplenomegaly, osteoporosis, neurologic symptoms

A

Gaucher’s disease (glucocerebrosidase deficiency)

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47
Q

Hereditary nephritis, sensorineural hearing loss, cataracts

A

Alport Syndrome (mutation in alpha chain of collagen IV)

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48
Q

Hyperphagia, hypersexuality, hyperorality, hyperdocility

A

Kluver Bucy syndrome (bilateral amygdala lesion)

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49
Q

Hyperreflexia, hypertonia, + babinski sign

A

Upper motor neuron damage

50
Q

Hyporeflexia, hypotonia, atrophy, fasciculations

A

Lower motor neuron damage

51
Q

Hypoxemia, polycythemia, hypercapnia

A

Blue bloaters (chronic bronchitis: hyperplasia of mucous cells)

52
Q

indurated, ulcerated genital lesion

A

Nonpainful: Chancre (primary syphilis, Treponema pallidium) Painful w/ exudate: Chancroid (Haemophilus ducreyi)

53
Q

Infant with cleft lip/palate, microcephaly or holoprosencephaly, polydactyly, cutis aplasia

A

Patau’s syndrome (trisomy 13)

54
Q

Infant with failure to thrive, hepatosplenomegaly, and neurodegeneration

A

Niemann-Pick disease (genetic sphingomyelinase deficiency)

55
Q

Infant with hypoglycemia, failure to thrive, and hepatomegaly

A

Cori’s disease (debranching enzyme deficiency)

56
Q

Infant with microcephaly, rocker-bottom feet, clenched hands, and structural heart defect

A

Edwards’ Syndrome (trisomy 18)

57
Q

Jaundice, palpable distended non-tender gallbladder

A

Courvoisier’s sign (distal obstruction of biliary tree)

58
Q

Large rash with bull’s eye appearance

A

Erythema chronicum migrans from Ixodes tick bite (Lyme disease: Borrelia burgdorferia)

59
Q

Lucid interval after traumatic brain injury

A

Epidural hematoma (middle meningeal artery rupture)

60
Q

Male child, recurrent infections, no mature B-cells

A

Bruton’s disease (X-linked agammaglobulinemia)

61
Q

Mucosal bleeding and prolonged bleeding time

A

Glanzmann’s thrombasthenia (defect in platelet aggregation from lack of GpIIb/IIIa)

62
Q

Muffled heart sounds, distended neck veins, hypotension

A

Beck’s triad of cardiac tamponade

63
Q

Multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumerary teeth

A

Gardner’s syndrome (subtype of FAP)

64
Q

Myopathy (infantile hypertrophic cardiomyopathy), exercise intolerance

A

Pompe’s disease (lysosomal alpha-1,4-glucosidase deficiency)

65
Q

Neonate with arm paralysis following difficult birth

A

Erb-Duchenne palsy (superior trunk [C5-6] brachial plexus injury: “waiter’s tip”)

66
Q

No lactation postpartum, absent menstruation, cold intolerance

A

Sheehan’s syndrome (pituitary infarction)

67
Q

Nystagmus, intention tremor, scanning speech, bilateral internuclear opthalmoplegia

A

Multiple Sclerosis

68
Q

Oscillating slow/fast breathing

A

Cheyne-Stokes respirations (central apnea in CHF or increase intracranial pressure)

69
Q

Painful blue fingers/toes, hemolytic anemia

A

Cold agglutinin disease (autoimmune hemolytic anemia caused by Mycoplasma pneumoniae, infections mononucleosis)

70
Q

Painful, pale, cold fingers/toes

A

Raynaud’s phenomenon (vasospasm in extremities)

71
Q

Painful, raised red lesions on pad of finger/toes

A

Osler’s node (infective endocarditis, immune complex deposition)

72
Q

Painless erythematous lesions on palms and soles

A

Janeway lesions (infective endocarditis, septic emboli/microabscesses)

73
Q

Painless jaundice

A

Cancer of pancreatic head obstructing bile duct

74
Q

Palpable purpura on buttocks/legs, joint pain, abdominal pain (child), hematuria

A

Henoch-Schonlein purpura (IgA vasculitis affecting skin and kidneys)

75
Q

Pancreatic, pituitary, parathyroid tumors

A

MEN1 (auto-dominant)

76
Q

Periorbital and/or peripheral edema, proteinuria, hypoalbuminemia, hypercholesterolemia

A

Nephrotic syndrome

77
Q

Pink complexion, dyspnea, hyperventialion

A

Pink Puffer (emphysema: centriacinar [smoking], panacinar [alpha-1-antitrypsin] deficiency)

78
Q

Polyuria, renal tubular acidosis type II, growth failure, electrolyte imbalances, hypophosphatemic rickets

A

Fanconi’s Syndrome (proximal tubular reabsorption defect)

79
Q

Positive anterior “drawer sign”

A

Anterior Cruciate ligament injury

80
Q

Pruritic, purple, polygonal planar papules and plagues (6 P’s)

A

Lichen Planus

81
Q

Ptosis, miosis, anhidrosis

A

Horner’s syndrome (sympathetic chain lesion)

82
Q

Pupil accomodates but doesn’t react

A

Argyll Robertson pupil (neurosyphilis)

83
Q

Rapidly progressive leg weakness that ascends following GI/upper respiratory infection

A

Guillan-Barre syndrome (actue autimmune inflammatory demyelinating polyneuropathy)

84
Q

Rash on palms and soles

A

Coxsackie A, secondary Syphilis, Rocky Mountain Spotted Fever

85
Q

Recurrent colds, unusual eczema, high serum IgE

A

Hyper-IgE syndrome (Job’s Syndrome: neutrophil chemotaxis abnormality)

86
Q

Red “current jelly” sputum in alcoholic or diabetic patients

A

Klebsiella pneumoniae

87
Q

Red “currant jelly” stools

A

Acute mesenteric ischemia (adults), intussesception (infants)

88
Q

Red, itchy, swollen rash of nipple/areola

A

Paget’s disease of the breat (represents underlying neoplasm)

89
Q

Red urine in the morning, fragile RBC’s

A

Paroxysmal nocturnal hemoglobinuria

90
Q

Renal Cell carcinoma (Bilateral), hemangioblastomas, angiomatosis, pheochromocytoma

A

von Hippel-Lindau Disease (dominant tumor suppressor gene mutation)

91
Q

Resting tremor, rigidity, akinesia, postural instability

A

Parkinson’s Disease (nigrostriatal dopamine depletion)

92
Q

Retinal hemorrhages with pale centers

A

Roth’s spots (bacterial endocarditis)

93
Q

Severe jaundice in neonate

A

Crigler-Najjar syndrome (Congenital unconjugated hyperbilirubinemia)

94
Q

Severe RLQ pain with palpation of LLQ

A

Rovsing’s Sign (acute appendicitis)

95
Q

Severe RLQ pain with rebound tenderness

A

McBurney’s sign (appendicitis)

96
Q

Short stature, increased incidence of tumors/leukemia, aplastic anemia

A

Fanconi’s Anemia (genetic loss of DNA crosslink repair; often progresses to AML)

97
Q

Single palmar crease

A

Simian crease (Down Syndrome)

98
Q

Situs inversus, chronic sinusitis, bronchiectasis, infterility

A

Kartagener’s Syndrome (Dynein arm defect –>primary ciliary dyskinesia)

99
Q

Skin hyperpigmentaiton, hypotension, fatigue

A

Addison’s disease (primary adrenocortical insufficiency causes increased ACTH and alpha-MSH production)

100
Q

Slow, progressive muscle weakness in boys

A

Becker’s Muscular Dystrophy (X-linked missense mutation in Dystrophin; less severe than Duchenne’s)

101
Q

Small, irregular red spots on buccal/lingual mucosa with blue-white centers

A

Koplik Spots (measles; rubeola virus)

102
Q

Smooth, flat, moist, painles white lesions on genitals

A

Condylomata lata (secondary syphilis)

103
Q

Splinter hemorrhages in fingernails

A

Bacterial endocarditis

104
Q

Strawberry Tongue

A

Scarlet fever, Kawasaki disease, toxic shock syndrome

105
Q

Streak ovaries, congenital heart disease, horseshoe kidney, cystic hygroma at birth, short stature, webbed neck, lymphedema

A

Turner Syndrome (45,XO)

106
Q

Sudden swollen/painful big toe joint, tophi

A

Gout/podagra (hyperuricemia)

107
Q

Swollen gums, mucosal bleeding, poor wound healing, spots on skin

A

Scurvy (vit C deficiency: can’t hydroxylate proline/lysine for collagen syntheiss)

108
Q

Swollen, hard, painful finger joints

A

Osteoarthritis (osteophytes on PIP [Bouchard’s nodes], DIP [Heberden’s nodes])

109
Q

Systolic ejection murmur (crescendo-decrescendo)

A

Aortic stenosis

110
Q

Thyroid and parathyroid tumors, pheochromocytoma

A

MEN2A (auto Dominant ret mutation)

111
Q

Thyroid tumors, pheochromocytoma, ganglioneuromatosis

A

MEN 2B (auto-dominant ret mutation)

112
Q

Toe extension/fanning upon plantar scrape

A

Babinski sign (UMN lesion)

113
Q

Unilateral facial droopooping involving forehead

A

Facial nerve (LMN CN VII palsy)

114
Q

Urethritis, conjunctivitis, arthritis in a male

A

Reactive arthritis associated with HLA-B27

115
Q

Vascular birthmark (port wine stain)

A

Hemangioma (Benign, but associated with Sturge-Weber syndrome)

116
Q

Vomiting blood following gastroesophageal lacerations

A

Mallory-Weiss syndrome (alcoholic and bulimic patients)

117
Q

Weight loss, diarrhea, arthritis, fever, adenopathy

A

Whipple’s disease (Tropheryma whippeleii)

118
Q

“Worst headache of my life”

A

Subarachnoid hemorrhage

119
Q

HTN and hyperkalemia

A

Renal failure.

120
Q

SHIPP

A

Rx that cause Lupus like symptoms: S: Sulfasalazine H: Hydralazine I: Isoniazid P: Procainamide P: Phenytoin

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