Classes Of Catalysis

Question 1

Strain

Answer 1

(Stabilize bonds in high energy 3D structure)
Substrate is in a different shape that is less favorable
different from what it is normally

Question 2

Cage Effect

Answer 2

(Bind two substrates in the correct orientation for reaction, increasing their local concentration)
Two substrates in the active site at the same time

Question 3

Acid-Base

Answer 3

(Give and take protons from/to substrate using amino acids or an active site water)
Look for arrows that show the bonds between the hydrogen and amino acids/substrates are being broken/formed

Question 4

Covalent

Answer 4

(Substrate(s) are going to be covalently bonded to the enzyme at some point in the reaction)
There should be a solid line between one of the amino acids that make the active site

Question 5

Metal Ion

Answer 5

(Metals are used to promote proper orientation of bound substrates and can aid in redox reactions)
There is a metal ion in the active site