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Classes Flashcards

1
Q

Citalopram

A

SSRI
Least DI
>40mg = QT prolong

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2
Q

Trimipramine

A

3-TCA

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3
Q

Fluvoxamine

A

SSRI
Shortest half life
Only for OCD
Sedating

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4
Q

Fluoxetine

A

SSRI
Longest T1/2
Most activating/Wgt neutral
Highest DI

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5
Q

Amitriptyline

A

3-TCA

Migraine Prophylaxis

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6
Q

Imipramine

A

3-TCA

Txt - PEDS enuresis/depression

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7
Q

Escitalopram

A

SSRI
Least DI
More potent than Citalopram - minor QT prolong

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8
Q

Vilazodone

A

Other SSRI

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9
Q

Nortriptyline

A

2-TCA

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10
Q

Vortioxetine

A

Other SSRI
TXT - MDD
Can D/C rapidly

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11
Q

Clomipramine

A

3-TCA

FDA - OCD only

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12
Q

Desipramine

A

2-TCA

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13
Q

Sertraline

A

SSRI

PTSD - MDD

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14
Q

Doxepin

A

3-TCAs

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15
Q

Paroxetine

A

SSRI
Most EPS SE’s
Worst Wgt gain
Teratogenic

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16
Q

Protriptyline

17
Q

Duloxetine

A

SNRI
Severe/refrac depression
Dose dependent - NEPI reup
Doesnt increase BP like other SNRI

18
Q

Venlafaxine

A

SNRI - dose depend - >225 NEPI - <150 Sero
1st line txt PTSD
Severe/refrac depression
Renal/liver dysfx adjust

19
Q

Desvenlafaxine

20
Q

Levomilnacipran

A

SNRI - Strongest reup inhib of NEPI
Depression
Liver dysfx CI

21
Q

Milnacipran

A

SNRI

FDA fibromyalgia

22
Q

Bupropion

A

NDRI - Nepi/Dopa reup inhib

Less sex dys SEs

23
Q

Trazodone

A

Serotonin recep antag and
h1 and a1 as well - sleepy/ortho hotn
Combo w/ ssri/snri for sleep d/o and depression
Mod reup inhib of Sero

24
Q

Mirtazapine

A

Sera recep antag - no reup efx
Txt MDD
Renal adjust

25
Q

Nefazodone

A

Sero recep antag - and alpha 1
Inhibits reup sero/nepi
Liver dysfx adjust

26
Q

Phenelzine

A

MAOI-A - blk enz degradation of Nepi/Dopa/Sero

27
Q

Tranylcypromine

A

MAOI-A - blk enz degradation of Nepi/Dopa/Sero
Nonselective
Food - tyramine DI

28
Q

Selegiline

Pharm 4 (3 decks)

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