Classes #3-#7: Descriptive Epidemiology and Measures of Disease Frequency Flashcards

1
Q

What are the 3 different surveillance systems used by epidemiologist?

A
  • Passive Surveillance System
  • Active Surveillance System
  • Syndromic Surveillance System
    • Dr. Segars also discussed Biosurveillance (human, plant, animal, and environment)
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2
Q

What is a passive surveillance system?

A

Relies on a healthcare system to follow regulations on required reportable diseases/conditions (e.g: a doctor reporting a disease in his patients).
*public health system passively waits for reports to come in, in order to track disease frequency/occurrence over time and within populations.

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3
Q

Describe what an active surveillance system is.

A

public health officials go out into the community to search for new disease/condition cases.

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4
Q

Define what a syndromic surveillance system is.

A

A system that looks for pre-defined signs/symptoms of patients, either being reported or evaluated.

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5
Q

What do you think is the most critical element that must be defined before any of the W’s of descriptive epidemiology can be accomplished?

A

“Case” Definition – The definition of disease. The epidemiologist has to know what they’re looking for.
This is called Diagnostic Criteria – In medicine this is called set criteria.

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6
Q

What is a “case” definition?

A

Is a set of uniform criteria used to define a disease/condition for public health surveillance.
>enable public health to classify and count cases consistently across reporting jurisdictions
>while the list of reportable conditions varies by state, the CSTE has recommended that state health departments report cases of selected diseases to NNDSS
>every year, case definitions are updated using CSTE’s Position Statements. They provide uniform criteria of nationally notifiable infectious and non-infectious conditions for reporting purposes.
>Epidemiologists and Healthcare providers must carefully and consistently define and execute exactly HOW we will detect (diagnose) what we want to, or have to, count; accurately! (Confirmed vs. Probable case definitions)

(The reported Criteria changes with knowledge of the disease, which is handle and carried out by the CSTE)

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7
Q

What is the definition of epidemic?

A

The occurrence of disease clearly in excess of normal expectancy.
>community/period clearly defined
>goal is to capture disease as early as possible

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8
Q

What is the definition of outbreak (cluster)?

A

An epidemic limited to a localized increase in the occurrence of disease. (sometimes interchanged with “cluster”)

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9
Q

What is the definition of endemic?

A

The constant presence of a disease within a given area or population in excess of normal levels in other areas. (e.g: HIV in Africa is an Endemic)

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10
Q

What is a Pandemic?

A

An epidemic occurring over a very wide area involving a large number of people.
>many times multi-region or multi-national
>when disease crosses country to country

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11
Q

What is “The Epidemic Curve”?

A

A visual depiction created during an outbreak/epidemic of the # of cases; by date of onset.

> Visually Depicts

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12
Q

What tool do epidemiologist construct/use to help form hypotheses on routes of transmission, probable exposure period, and incubation period (may help identify/eliminate causes)?

A

An Epidemic Curve

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13
Q

What type of epidemiology is used to determine if a site/location is experiencing disease occurrence MORE FREQUENTLY THAN USUAL (for the location)?

A

Descriptive Epidemiology

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14
Q

What are the 3 basic types of relative measures of disease frequencies utilized by epidemiologists (either within a group or between groups)?

A

1) Ratios
2) Proportions
3) Rates

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15
Q

How do you calculate a ratio, and what does it tell you?

A

A ratio is the division of 2 unrelated numbers.
>the numerator is not part of the denominator
> e.g: YES / NO

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16
Q

What is a proportion and how do you calculate it?

A

A proportion is the division of 2 related numbers.
>the numerator is a subset of the denominator
>e.g: YES / ALL

17
Q

What is a rate and how do you calculate it?

A

A rate is the division of 2 numbers with TIME incorporated into the denominator.
>Rate is the easiest because it has time in the denominator. Time is important because we want to make sure we are comparing apples to apples.

18
Q

What is infectivity and how do you calculate it?

A

Infectivity –> is the ability to invade a patient (host)

              formula = #infected / # susceptible (at risk)
19
Q

What are the 3 measure in infectious disease?

A

Infectivity – the ability to invade a patient (host)

Pathogenicity – the ability to cause clinical disease

Virulence – the ability to cause death

20
Q

What is pathogenicity and how do you calculate it?

A

Pathogenicity is the ability to cause clinical disease.

                 formula = # with clinical disease / # infected
21
Q

What is virulence and how is it calculated?

A

Virulence is the ability to cause death.

                    formula = # of deaths / # with infectious disease
22
Q

What are the 3 key factors in comparing measures of disease frequency between groups?

A

1) # of people affected/impacted (frequency)
2) Size of the source population
3) Length of time the population (or individuals in the population) is/are followed.

23
Q

The _____ and time period of evaluation MUST be equal to adequately and appropriately compare frequencies between groups.

A

Population Size

24
Q

What is the INCIDENCE in measures of disease frequency?

A

The new cases of disease.

25
Q

What is the PREVALENCE in the measure of disease frequency?

A

Is the existing cases of disease + new cases of disease.

26
Q

How do you calculate incidence (risk, attack rate, cumulative incidence)?

A

incidence rate = # new cases of disease / # persons at risk for the disease

**remember to subtract out (from the starting population), those who already have the disease or are immune to the disease (not “at risk”).

**Not very precise for dynamic populations (fluctuations)

27
Q

How do you calculate incidence density?

A

incidence density = # of new cases of a disease / total person-time of population at risk for the disease

** appropriate for dynamic populations and fluctuating “at risk” periods

28
Q

What is the calculation for prevalence?

A

prevalence = # of existing cases of a disease/# of persons in population

  • *Time frames for numerator/denominator must be the same
  • *The denominator includes those with the disease and those at risk of getting the disease.
  • *Point Prevalence – prevalence at a given point in time
  • *Period Prevalence – prevalence over a given period of time