Class 38: Reviewing Medical Literature

Question 1

A unique identifier # assigned by clinical trials.gov once research protocol is submitted prior to study initiation.

Purpose was to reduce publication bias

Answer 1

National clinical trials number (NCT#)

Question 2

All checklists found at:

Answer 2

Equator network

Question 3

The checklist we use for interventional studies:

Answer 3

CONSORT

There are also “extensions” for cluster trials,pragmatic, etc.

Question 4

A digital identifier number to easily find the number of the study.

Answer 4

DOI

This can help you to discern btw the follow up studies and editorial comments. So you have the whole story all at once

Question 5

Checklist for Systematic reviews of multiple randomized trials

Also, interventional trials

Answer 5

PRISMA

Question 6

Checklist used for all observational studies:

Answer 6

STROBE- wont find what randomization was used…b/c its obs study!

Also has extensions

Question 7

Checklist for non-randomized studies behavioral public health studies

Answer 7

TREND

Question 8

Checklist for Tumor marker prognostic studies

Answer 8

REMARK

Question 9

Checklist for genetic risk prediction studies

Answer 9

GRIPS

Question 10

Diagnostic studies checklist

Answer 10

STARD

Question 11

Checklist for systematic reviews of multiple diagnostic studies

Answer 11

QUADAS-2