Class 23: Valve Disorders Flashcards

1
Q

what is infective endocarditis

A
  • infection of the heart valves or endocardial surface of the heart
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2
Q

inflammation from infective endocarditis affects the ________

A

cardiac valves

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3
Q

what causes infective endocarditis

A
  • bacteria most common

- also viruses, & fungi

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4
Q

what are the primary lesions of infective endocarditis

A
  • vegetations
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5
Q

what do the vegetations of infective endocarditis consist of

A
  • fibrin
  • platelets
  • microbes
    that adhere to the valve surface or endothelium
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6
Q

what happens if portions of the vegetations from infective endocarditis are lost intro circulation

A
  • can cause emboli
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7
Q

what do emboli result in from infective endocarditis

A
  • strokes, kidney disease, damage to spleen, pulmonary emboli, limb infarction
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8
Q

what are risk factors for infective endocarditis

A
  • IV drug use
  • prosthetic valves
  • acquired valve disease (ex. aortic stenosis)
  • congenital heart disease
  • pacemakers
  • marfan syndrome
  • cardiomyopathy
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9
Q

what are symptoms of infective endocarditis

A
  • low fever
  • chills
  • weakness
  • malaise & fatigue
  • anorexia
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10
Q

what are oslers nodes

A
  • tender, painful red or purple pea-ized lesions on fingertips or toes
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11
Q

what are janeways lesions

A
  • flat, painless, small red spots on palms & soles
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12
Q

what are specific findings w infective endocarditis

A
  • splinter hemorrhages
  • petechiae
  • oslers nodes
  • janeways lesions
  • roths spots
  • murmur
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13
Q

what are splinter hemorrhages

A
  • occur in nail beds
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14
Q

why might there be petechiae with infective endocarditis

A
  • fragmentation & microembolization of vegetative lesions
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15
Q

what are roth’s spots

A
  • hemorrhagic retinal lesions
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16
Q

what valves are most effected in infective endocarditis

A
  • aortic & mitral
17
Q

what may indicate damage to the spleen

A
  • sharp, left uppe quad pain with splenomegaly
18
Q

what might indicate kidney damahge

A
  • flank pain
  • hemauria
  • azotemia
19
Q

what might indicate emboli in small peripheral vessels

A
  • gangrene
20
Q

what might indiciate emboli in the brain

A
  • hemiplegia
  • atazia
  • aphasia
  • visual changes
  • change in LOC
21
Q

describe drug therapy for infective endocarditis

A
  • depends on the causitive agent for infection = use blood cultures to determine