CLASS 2 - Successful Aging Flashcards
What are the 3 “R’s” that helped Esther get to 100yrs old?
- Resilience
- Resourcefulness
- Resolution
In the US, the number of centinarians have increased from 38,300 in 1990 to ___ in 2009.
96,548
True or false? Centinarians are 20x likely to have a long-lived relative than the average person?
True
According to the Swedish twin study, what percent of longevity is due to genetics?
80%
Esther Tuttle’s advice for aging?
“You have to work, be cheerful, and look for something fun to do. It’s a whole attitude.”
Esther Tuttle’s regime? (4)
- Careful diet
- Hard work
- Regular exercise
- Long list of community service
A study of centinarians in Sardinia found they are: (4)
- Physically active
- Have extensive social networks
- Maintain strong ties with family & friends
- Less depressed than the average 60yr old
T/F: Optimists live long than pessimists.
True
T/F: Pessimists are less likely to be overweight, smoke cigarettes, and avoid exercise.
False, they are MORE likely.
T/F: Optimists are less likely to have high BP, diabetes, and high cholesterol.
True
How much does genetics determine the againg process?
20-30%
Name at least 3 predictors of successful aging (8).
- Genetics
- Culture and gender
- Physical and social environment
- Socioeconomic status
- Life events
- Psychological attributes
- Lifestyle choices and behaviors
- Health and social services
What are the two modern biological theories of aging?
- Programmed theory
- Damage theory
According to the programmed theory, aging follows a ___ ___ that depends on changes in gene expression.
Biological timetable
According to the damage theory, ___ ___ to living organisms would induce cumulative damage at various levels.
Environmental stress
Out of the programmed and damage theory which one has more studies?
Damage theory (500+ vs 75)
What are the sub-categories of the programmed theory? (4)
- Programmed longevity
- Endocrine theory
- Immunological theory
- Hayflick Immunological theory
Which subcategory is this?
Aging is the result of a sequential switching on and off of certain genes, with a senescence being defined as the time when age-associated deficits are manifested.
Programmed longevity
Which subcategory is this?
Biological clocks act through hormones to control the pace of aging. Supported by recent studies showing that insulin plays a key role in the hormonal regulation of aging.
Endocrine theory
Which subcategory is this?
The immune system is programmed to decline over time, which leads to an increased vulnerability to infectious disease and thus aging and death.
Immunological theory
Which subcategory is this?
Normal human cells can only replicate and devide 40-60 times, and will afterwards be broken down by programmed cell death (apoptosis).
Hayflick Immunological Theory
What are the subcategories for the Damage theory? (5)
- Wear and Tear Theory
- Rate of Living Theory
- Cross-linking Theory
- Free Radical Theory
- Somatic DNA Damage Theory
Which subcategory is this?
Cells and tissues have vital parts that wear out from repeated use resulting in aging.
Wear and Tear Theory