Class 2 Complications of Labor Flashcards
What is “Term”?
Single pregnancy 37-42 completed weeks
Preterm labor definition.
Regular contractions at least every 10 minutes resulting in cervical change prior to 37 weeks.
Low birth weight (LBW)
infant < 2500g
Very low birth weight (VLBW)
Infant < 1500g
Infant mortality for < 24 weeks, < 30 weeks, >34 weeks?
- 90% death
- 90% survival
- 98% survival
Survival can increase ___% each day between weeks __ - ___.
- 5%
- 25 - 26
8 Premature comorbidities.
- intercranial hemorrhage
- Ischemic cerebral damage
- Immature metabolism
- Hypoglycemia
- Hyperbilirubin
- Necrotizing enterocolitis
- respiratory distress
- Sepsis
When is premature respiratory distress seen? And what exacerbates the symptoms?
- All infants < 27 weeks 0% by 36 weeks
- Intrapartum hypoxia and maternal stress
What 3 bacteria causes preterm labor?
- Group B Strep
- Gonorrhea
- Bacterial vaginosis
When is C-section safer than vaginal delivery for PTL?
Breech
How does an epidural help in PTL?
- Avoids precipitous delivery
- Decrease risk of ICH
- Avoids maternal pushing against incomplete cervix
What are tocolytics?
- Drugs used to stop or slow contractions
- Used between 20-34 weeks and <2500 g
Are tocolytics used for long term or short term use and why?
- Short term
- Allow time for steroids to aid in lung maturation or transfer to a NICU
How doe ethanol work as a tocolytic?
- Inhibits release of ADH and Oxytocin
- Direct effect on myometrium
- Interference with prostaglandins
3 risks of ethanol?
- Intoxication
- LOC
- Aspiration
How does methylxanthines work as tocolytics and what is the side effect?
- Phosphodiesterases increase cAMP and cause uterine muscle relaxation
- Narrow therapeutic margin
How do calcium channel blockers work as tocolytic?
-Decrease free calcium = decreased contractility
Name a calcium channel blocker tocolytic.
-Nifedipine