Class 1C (Anti-Arrythmics)

Question 1

What is the basic MOA of class 1C drugs?

Answer 1

It will block fast gated sodium channels of any shape, as a result no effects in the APD or ANS.

Question 2

What is a class 1C drug? What’s it used for?

Answer 2

Flecainide, limited in its use due to being pro-arrythmic and propensity to cause sudden death.

Question 3

When would you use a class 1C drug?

Answer 3

When all else fails and the patient is about to die anyway, it saves the lives of some people but is not first line.