Class 1 Flashcards

1
Q

4 classes of biological molecules

A

proteins
nucleic acids
carbohydrates
lipids

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2
Q

what are proteins

A

they are linear polymers of L-amino acids that are joined by peptide bonds

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3
Q

how are peptide bonds formed

A

they are formed though condensation reactions
- when the carboxyl group of one molecule reacts with the amino group of the other molecule, releasing a molecule of water (H2O)

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4
Q

what are the functions of protein

A

regulation
signaling
transport
catalysis
movement
structure

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5
Q

what are nucleic acids

A

the information molecules in the cell
- monomers
- phosphate group + sugar + base called a nucleotide
-DNA & RNA are the two main ones

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6
Q

what is DNA

A

double helix made up of 2 strands that are polymers of deoxyribonucleotides

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7
Q

what holds DNA together, what bases connect

A

non-covalent interactions between bases
A –> T
G –> C

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8
Q

What is RNA

A

single- stranded polymer of ribonucleotides contains bases A,G,C and U (replaces T)

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9
Q

nucleic acids are polymer of nucleotides that are joined together by…?

A

phosphodiester bonds (catalyzed by DNA or RNA polymerase)

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10
Q

central dogma of molecular biology

A

information flows from DNA to RNA to protein

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11
Q

DNA –> DNA

A

replication

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12
Q

DNA –> RNA

A

transcription by RNA polymerase

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13
Q

RNA – > Protein

A

Translation

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14
Q

Carbohydrates are..?

A

linear or branched polymers of monosaccharides

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15
Q

4 monosaccharide characteristics

A

1) can be classified according to the number of cartoon atoms
2) Most sugars are in the cyclic form(ring form), not in the open-chain (acrylic form)
3)they are join together to form di, olio, and poly saccharides
-onyl mono and di are sugars
4) There are thousands of different carbohydrates, which can be linked together in chains and form branches via glycosidic bonds (Glycogen or Starch synthase)

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16
Q

what makes up lactose

A

galactose + glucose

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17
Q

what makes up sucrose

A

glucose + fructose

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18
Q

maltose

A

glucose + glucose

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19
Q

what are the polysaccarides

A

branched glycogen(from animal)
starch (plant sources)
unbranched cellulose(plant sources

20
Q

some functions of carbohydrates

A

fuel source, glucose stored as glycogen in animals
structural molecules(cellulose)
signaling ( cell-cell recognition)
lubricants

21
Q

what are lipids

A

water-insoluble molecules that are highly soluble in organic solvents

22
Q

fatty acids

A

simplest form of lipid
long hydrocarbon chain +carboxyl group
most commonly used as fuel

23
Q

triglycerols

A

storage form of fatty acids

24
Q

Fats

A

consist of glycerol and 3 fatty acids
created via 3 condensation reactions creating ester linkages that connect carboxyl groups to the hydroxyl groups in glycerol

25
membran lipids
phospholipids
26
glycolipids
bound to carbohydrates, membrane components
27
steroids
cholesterol is a steroid -4 fused hydrocarbon rings with a steroid at on end and a hydroxyl group on the other, cell membrane and hormone
28
emphatic nature of lipid
hydrophilic head - can dissolve in water hydrophobic tails - cannot dissolve in water
29
emphatic nature of lipid
hydrophilic head - can dissolve in water hydrophobic tails - cannot dissolve in water
30
6 functions of lipids
• Major component of membrane (phospholipids) • Long term energy storage • Protection against heat loss (insulation) • Protection against physical shock • Protection against water loss • Chemical messengers (hormones)
31
covalent bonds
bonds in which the electrons are shared by the participating amino acids
32
peptide bond enzyme?
each amino acid is attached to another amino acid by a covalent bond enzyme: peptidyltransferase
33
phosphodiester bond enzyme?
a covalent bond in RNA and DNA that holds na polynucleotide chain together by joining a phosphate group at position 5 in the pentose sugar of one nucleotide to the hydroxyl group at position 3 in the pentose sugar of the next nucleotide enzyme: DNA or RNA polymerase
34
ester bonds enzyme?
triglycerides are lipids inciting of one glycerol molecule bonded with three fatty acids molecules. The bonds between the molecules are covalent and are called ester bonds enzyme: actyltransferase
35
glycosidic bond enzyme?
carbohydrates are made up of monosaccharides linked together into polysaccharide chains by a type of covalent bond known as a glycosidic bond enzyme: glycogen synthase
36
4 main types of non covalent bonds
1) hydrogen bonds 2) ionic bonds, or electrostatic interactions 3) van der Waals interactions 4) hydrophobic bonds
37
why is water dipolar and cohesive
1) water is dipolar because it has an uneven distribution of electrons between the hydrogen and oxygen - oxygen nucleus attracts e- stringer than hydrogen resulting in unequal share and dipoles 2) it forms hydrogen bonds with each other and other polar molecules and acts as a solvent 3) cohesive bc the hydrogen bonds make water very attractive to each other
38
what is a hydrogen bond -its property?
a hydrogen bond is an attractive force between a partially positive charged hydrogen and a partially negative charged atom (oxygen or nitrogen) -hydrogen bonds between two molecules are disrupted by water when water forms hydrogen bonds with these molecules -the polarity of water and its ability to form hydrogen bonds renders it a solvent for any charged or polar molecule
39
Is water polar or non polar
polar solvent (solvent of life): dissolves charged or polar compounds by replacing solute-solute H-bonds with solute-water H-bonds
40
hydrophilic
Compounds that dissolve easily in water are hydrophilic (water soluble).
41
hydrophobic
Non-polar molecules such as lipids are hydrophobic; side chains of some amino acids are referred to as “hydrophobic”. (water insoluble)
42
amphipathic
molecules have polar or charged regions, as well as non-polar regions.
43
ionic bonds/electrostatic interactions
a weak interaction between ions having opposite charges. water weakens these
44
van der Waals interactions
the attraction between two molecules based on the transient electron asymmetry around an atom that induced a complimentary asymmetry in a nearby molecule - short range, molecules are neither polar nor charged, very weak
45
hydrophobic interactions
the process in which non polar molecule in aqueous solutions are driven together because of the resulting increase in entropy of water molecules -powers membrane formation and protein folding