CKD Epidemiology

Question 1

Why might you be mislead by using blood creatinine levels only to estimate GFR?

Answer 1

Other factors need to be taken into account:
Age
Muscle mass (gender can be used)
Black or White ethnicity

Question 2

GPs recently started using formulas to predict kidney function. What have been some of the outcomes of this?

Answer 2

This has improved the recognition of true cases or at least assigning patients to the correct stage. This means that there has been a lower number of referrals with a benign reduction in GFR but has also meant that there has been a reduction in the number of people presenting at a later stage in their disease progression.. They are not useful for acute renal failure situations.

Question 3

Rank these by their survival likelihood from worst to best.

Glomerulonephritis, Interstitial nephritis, Polycystic kidney disease, Hypertensive nephrosclerosis

Answer 3

Polycystic kidney disease
Glomerulonephritis
Hypertensive nephrosclerosis
Interstitial nephritis

Question 4

On microscopic examination or imaging what is the key feature you would see in the case of IgA nephropathy

Answer 4

Focal antibody deposits