Citric acid cycle

Question 1

What happens to pyruvate before it can enter the citric acid cycle? What is the waste product?

Answer 1

It is broken down to Acetyl CoA by oxidative decarboxylation.
Waste product is carbon dioxide

Question 2

What is the enzyme involved in the break down of pyruvate Where is it located?

Answer 2

Pyruvate dehydrogenase, it is located in the mitochondrial matrix

Question 3

How many NADH are produced in the oxidation of pyruvate?
Per pyruvate
Per glucose

Answer 3

1 NADH per pyruvate molecule

2 NADH per glucose molecule

Question 4

What does acetyl coA do?

Answer 4

It feeds two carbon units in to the citric acid cycle.

This turns the 4 carbon oxaloacetate in to a 6 carbon citric acid

Question 5

Coenzyme A is an activated carrier molecule. What 3 things does it carry?

Answer 5

1. Acetyl groups
2. Energy (bonds with additional phosphate)
3. Electrons (H)

Question 6

Where does the citric acid cycle take place?

Answer 6

In the mitochondrial matrix

Question 7

What does ONE TURN of the citric acid cycle generate?

Answer 7

3 NADH
1 FADH2
1 ATP

Question 8

What does ONE GLUCOSE molecule generate from the citric acid cycle?

Answer 8

6 NADH
2FADH2
2ATP

Question 9

Waste product of citric acid cycle?

Answer 9

CO2

Question 10

Which stages produce NADH?

Answer 10

3 4 and 8

Question 11

Which stage produces FADH2?

Answer 11

6

Question 12

Where is ATP made?

Answer 12

stage 5

Question 13

What is made and converted in to ATP in TCA?

Answer 13

GTP