Citric Acid Cycle Flashcards
What is step 1 of the citric acid cycle and what are the reactants, products, enzymes and extra details?
Reactant: Acetyl CoA + oxaloacetate
Product: citrate
Enzyme: citrate synthase
Details: N/A
What is step 2 of the citric acid cycle and what are the reactants, products, enzymes and extra details?
Reactant: citrate
Product: isocitrate
Enzyme: aconitase
Details: one water lost and one gained
What is step 3 of the citric acid cycle and what are the reactants, products, enzymes and extra details?
Reactant: isocitrate
Product: alpha-ketoglutarate
Enzyme: isocitrate dehydrogenase
Details: uses one NAD+ produces NADH + CO2
What is step 4 of the citric acid cycle and what are the reactants, products, enzymes and extra details?
Reactant: alpha-ketoglutarate
Product: succinyl CoA
Enzyme: ketoglutarate dehydrogenase
Details: uses one NAD+ produces NADH + CO2
What is step 5 of the citric acid cycle and what are the reactants, products, enzymes and extra details?
Reactant: succinyl CoA
Product: succinate
Enzyme: succinyl CoA synthase
Details: uses one phosphate produces GTP
What is step 6 of the citric acid cycle and what are the reactants, products, enzymes and extra details?
Reactant: succinate
Product: fumarate
Enzyme: succinate dehydrogenase
Details: uses one FAD produces FADH2
What is step 7 of the citric acid cycle and what are the reactants, products, enzymes and extra details?
Reactant: fumarate
Product: malate
Enzyme: fumarase
Details: one water gained
What is step 8 of the citric acid cycle and what are the reactants, products, enzymes and extra details?
Reactant: malate
Product: oxaloactate
Enzyme: malate dehydrogenase
Details: uses one NAD+ produces NADH
Identify reactions that involve electron carriers.
There are two types of electron carriers that are particularly important in cellular respiration: NAD (nicotinamide adenine dinucleotide, shown below) and FAD (flavin adenine dinucleotide). The reactions in which NAD and FAD gain or lose electrons are examples of a class of reactions called redox reactions.
Identify reactions that release CO2.
NAD+ conversion to NADH. Conversion of alpha-ketoglutarate to succinyl coenzyme using coenzyme A.
Describe links to other metabolic pathways from the citric acid cycle.
Others can include; glycolysis, oxidative phosphorylation, fatty acid oxidation.
General other processes: Amino acid metabolism, carbohydrate metabolism, biosythesis of secondary metabolites, energy metabolism, lipid metabolism.
What is FADH2?
What Are FADH2 and NADH? Flavin adenine dinucleotide, or FADH2, is a redox cofactor that is created during the Krebs cycle and utilized during the last part of respiration, the electron transport chain.
