Citocinas Flashcards

1
Q

Citocinas proinflamatorias

A

TNF-⍺ (activa macrofagos, permeabilidad vascular)
IL-1 (inflamación, fiebre y neutrófilos)
IL-6
IL-12
IFN-γ
IL-17

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2
Q

Citocinas que inducen alergias

A

IL-4 (promueve IgE por LinB)
IL-5 (estimula eosinófilos)
IL-13 (induce moco y hiperreactividad bronquial)

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3
Q

Citocinas que favorecen

A

TGF-β (suprime LinT)
IL-6 (promueve cel. tumorales e inflamación)
IL-10 (inhibe macrofagos)

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4
Q

Citocinas inmunosupresoras

A

IL-10 (inhibe macrofaos)
TGF-β (suprime LinT)

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5
Q

Interferones de tipo 1

A

IFN alfa & IFN beta
Respuesta intracelular
Median respuesta antiviral temprana

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6
Q

Interferon tipo 2

A

IFN gamma
Activa macrofagos, ayuda a formación de TH1 y promueve muerte celular (fasL)

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7
Q

Interferon tipo 3

A

IFN lambda (IFN-λ)
Secretado por células dendriticas

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