CIS High Yield Handouts Flashcards
Brown pigment stones tend to form in ____ ____ as a result of bacterial infections.
Bile duct
What are the 6 F’s for gallstones?
FHx Fair Fat Female Fertile (Forty)
What are protective modifications to prevent Gallstones?
Low carbohydrate diet Physical activity Cardio respiratory fitness Caffeinated coffee (women) High intake of Mg and polyunsaturated and monounsaturated fats in Men High fiber diet and statin ASA and NSIADs
What is ascending cholangitis?
Infection of the biliary tract secondary to bile duct obstruction or bile stasis, duodenal microorganism ascend
Due to choledocholithiasis, pancreatic/biliary neoplasm, postop strictures, choledocholithiasis cysts
What organisms are involved in ascending cholangitis?
Gram -: e. Coli, klebsiella, enterobacter
Gram +: enterococcus species
Anaerobes: bactericides fragility and clostridia
What is Charcot Triad?
Jaundice
Fever > 102
RUQ pain
What is Reynolds pentad?
Carcot’s triad + mental status changes and hypotension
What is the Rx of ascending cholangitis?
Endoscopic emergency -> Urgent ERCP (w/in 12-24 hours)
Diagnostic and therapeutic
What is the diagnostic study of choic for cholecystokininase due to cholelithiasis?
ultrasound
A HIDA scan may dx _______?
Biliary dyskinesia
What is the empiric antibiotic therapy for gram negative and anaerobic organism causing cholangitis?
- Beta-lactam/beta-lactam inhibitor: ampicillin, piperacillin, ticarcillin
—or 3rd gen. Cephalosporin + metronidazole
What labs should be ordered for a pt w/ cholangitis?
AST/ALT, alk phos, blood cultures, fractionated bilirubin, amylase/ lipase (pancreatitis)
—pre-procedure INR
—follow blood culture and bile cultures
What are possible complication of status post ERCP?
Pancreatitis
Ascending cholangitis
Less common: hemophilia, perforation
What is Mirizzi syndrome?
Common hepatic duct obstruction caused by an extrinsic compression from an impacted stone in the cystic duct
—presence of a cholecystenteric fistula
What is the normal diaphragm excursion?
3 to 5.5 cm