Circulation NCERT Flashcards
All living cells have to be provided with —-, O2 and other essential substances. Also, the waste or —- substances produced, have to be removed continuously for healthy functioning of tissues.
nutrients, harmful
Hence, It is essential to have efficient mechanisms for the —– to the cells and from the cells.
movement of these substances
Different groups of animals have evolved different methods for this transport. Simple organisms like —— and — circulate water from their surroundings through their body cavities to facilitate the cells to exchange these substances.
sponges and coelenterates
More complex organisms use — fluids within their bodies to transport such materials
special
—–is the most commonly used body fluid by most of the higher organisms including humans for this purpose.
Blood
Another body fluid, —-, also helps in the transport of certain substances.
lymph
Blood is a special connective tissue consisting of a —–, —- and —–.
fluid matrix, plasma and formed elements
Plasma is a —- coloured, viscous fluid constituting nearly —– of
the blood.
straw, 55 per cent
90-92 per cent of plasma is —–and proteins contribute—- per cent of it.
water, 6-8
——-, —- and —- are the major proteins in blood
Fibrinogens, Albumins, Globulins
Fibrinogens are needed for —— of blood.
clotting or coagulation
Globulins primarly are involved in —– of the body and the albumins help in —– .
defense mechanisms
osmotic balance
Plasma also contains small amounts of —- like Na+, Ca++, Mg++, HCO3 , Cl–, etc.
minerals
Glucose, ——, lipids, etc., are also present in the plasma as they are always in —in the body.
amino acids,
transit
Factors for coagulation or clotting of blood are also present in the plasma in an —- form.
inactive
Plasma without the ——- is called serum.
clotting factors
——, —- and —- are collectively called formed
elements and they constitute nearly —- per cent of the blood.
Erythrocytes, leucocytes and platelets
45
——– or — are the most abundant of all the cells in blood.
Erythrocytes or red blood cells (RBC)
A healthy adult man has, on an average, —- of RBCs mm–3 of blood.
5 millions to 5.5 millions
RBCs are formed in the —– in the adults.
red bone marrow
RBCs are devoid of — in most of the mammals and are —- in shape
nucleus , biconcave
They have a red coloured, iron containing —– called haemoglobin, hence the colour and name of these cells
complex protein
A healthy individual has —- gms of haemoglobin in every 100 ml of blood.
12-16 gms
____ molecules play a significant role in transport of
respiratory gases
Haemoglobin
RBCs have an average life span of —- after which they are destroyed in the —– (graveyard of RBCs).
120 days
spleen
—- are also known as white blood cells (WBC) as they are colourless due to the lack of haemoglobin.
Leucocytes
WBC are nucleated and are relatively lesser in number which averages —-mm–3 of blood.
6000-8000
Leucocytes are generally —–.
short lived
We have two main categories of WBCs
– ——– and ——–.
granulocytes and agranulocytes
Neutrophils, —- and basophils
are different types of granulocytes, while lymphocytes and monocytes
are the —— .
eosinophils
agranulocytes
Neutrophils are the most abundant cells (—-
per cent) of the total WBCs and —– are the least (0.5-1 per cent)
among them.
60-65
basophils
Neutrophils and monocytes (—– per cent) are phagocytic
cells which destroy —–entering the body.
6-8
foreign organisms
Basophils secrete
histamine, serotonin, heparin, etc., and are involved in —-
reactions.
inflammatory
Eosinophils (—- per cent) resist infections and are also associated with _____
2-3
allergic reactions
Lymphocytes (—–per cent) are of two major types –—–.Both of which are responsible for —– of the body.
20-25
‘B’ and ‘T’ forms
immune responses
Platelets also called ——-, are cell fragments produced from ——- (special cells in the bone marrow).
thrombocytes
megakaryocytes
Blood normally
contains —- platelets mm–3.
1.5 L to 3.5 L
Platelets can release a varietyof substances most of which are involved in the —–
coagulation or clotting of blood
A reduction in the number of —– can lead to clotting disorders which
will lead to excessive loss of —- from the body.
Platelets
blood
ABO grouping is based on the presence or absence of two ——- on the RBCs namely A and B.
surface antigens
Antigens are chemicals that can ——
induce immune response
Similarly, the —– of different individuals contain two —- antibodies
plasma, natural
Antibodies are —– produced in response to antigens
proteins
the blood of a donor has to be carefully matched
with the blood of a recipient before any blood transfusion to avoid severe problems of ——- (destruction of RBC).
clumping
group ‘O’ blood can
be donated to persons with any other blood group and hence ‘O’ group individuals are called ‘———-’.
universal donors
Persons with ‘AB’ group can accept blood from persons with ——.
Therefore, such persons are called ‘universal recipients’.
AB as well as the other groups of blood
Another antigen, the Rh antigen similar to one present in ———
(hence Rh), is also observed on the surface of RBCs of majority (nearly —- per cent) of humans. Such individuals are called Rh positive (Rh+ve)
and those in whom this antigen is absent are called Rh negative (Rh-ve).
Rhesus monkeys, 80
An Rh-ve person, if exposed to Rh+ve blood, will form —- against the Rh antigens.
specific antibodies
A special case of Rh —-(mismatching)
has been observed between the —- blood of a pregnant mother with Rh+ve blood of the foetus.
incompatibility
Rh-ve
Rh antigens of the foetus do not get exposed to
the Rh-ve blood of the mother in the — pregnancy as the two bloods are
well separated by the —-
first, placenta
During the delivery of the first child, there is a possibility of —- to small amounts of the Rh+ve blood from the foetus.
In such cases, the mother
starts preparing antibodies against — in her blood.
exposure of the maternal blood
Rh antigen
In case of Rh-ve mother’s subsequent pregnancies, the Rh antibodies from the mother (Rh-ve)
can leak into the blood of the foetus (Rh+ve) and —- RBCs.
destroy the foetal
Rh-ve blood could be fatal to the foetus or could cause severe —- and — to the baby. This condition is called —.
anaemia and
jaundice
erythroblastosis foetalis
Erythroblastosis foetalis can be avoided by administering—- to the mother immediately after the delivery of the first child.
anti-Rh antibodies
Blood exhibits coagulation or clotting
in response to —–.
an injury or trauma
Clotting is a mechanism to prevent —- from the body.
excessive loss of blood
a dark reddish brown scum formed at the site of a cut or an injury over a period of time is a —- formed mainly of a network of threads
called —- in which dead and damaged formed elements of blood are
trapped.
clot or coagulam,
fibrins
Fibrins are formed by the conversion of inactive fibrinogens in
the plasma by the —–.
enzyme thrombin
Thrombins, in turn are formed from
another —– called prothrombin.
inactive substance present in the plasma
An ———, thrombokinase, is required for the above reaction. This
complex is formed by a series of linked enzymic reactions (——-) involving a number of factors present in the plasma in an — state.
enzyme complex
cascade process
inactive
An injury or a trauma stimulates the —- in the blood to release
certain factors which activate the mechanism of coagulation.
platelets
Certain factors released by —- at the site of injury also can initiate
coagulation.
the tissues
—— ions play a very important role in clotting
Calcium