Circulation: Inflammatory Disorders Flashcards
a microbial infection of the endocardium
infective endocarditis (previously called bacterial endocarditis)
Patients at risk for infective endocarditis:
- abuse IV drugs
- have had valve replacements
- have experienced systemic infection
- have structural cardiac defects
Possible ports of entry for infecting organisms include:
- oral cavity
- skin rashes, lesions, or abscesses
- infections
- surgery or invasive procedures, including IV line placement
If vegetations of infective endocarditis become so large that blood flow through the valve is obstructed, the valve appears stenotic and then is very likely to what?
embolize
S&S of Infective Endocarditis:
- recurrent fevers from 99-103
- murmurs (regurgitant)
- anorexia and weight loss
- development of heart failure
- systemic emboizatoin
- petechiae
- splinter hemorrhages
- Olser’s nodes
- Janeway’s lesions
most common infective organism of Infective Endocarditis is:
- Streptococcus viridans
- staphylococcus aureus
Most common complication of Infective Endocarditis:
- Heart Failure
- Arterial embolization (occurs in half pts)
black longitudinal lines or small red streaks on the distal third of the nail bed
splinter hemorrhages
Prime diagnostic test for Infective Endocarditis:
- positive blood culture
- low H&H
Treatment for Infective Endocarditis:
- Antimicrobials (IV, 5-6wks)
*if ineffective
- surgical removal
Do anticoagulants prevent emolization from vegetations?
No
an inflammation or alteration of the pericardium (the membranous sav that encloses the heart)
Acute pericarditis
S&S of Pericarditis:
- grating pain that is aggravated by breathing (substernal precordial pain that ratiates to Left side of neck, shoulder, or back)
- pain is worse in supine position and may be relieved by sitting up and leaning forward
- high-pitched pericardial friction rub over left lower sternal border
- elevated WBC
- fever
- ST-T spiking
- A. Fib
Treatment of Acute Pericarditis:
- NSAIDs or corticosteroids
- sitting upright, slightly forward
- Pericardial drainage
- Monitor for pericardial effusion
S&S of chronic constrictive pericarditis:
- right sided HF
- elevated systemic venous pressure with jugular distention
- hepatic engorgement
- dependent edema
- exertional fatigue and dyspnea
- thickening of pericardiam (ECHO/CT)