Circadian rhythms BP Flashcards
Circadian rhythms
biological rhythms subject to 24 hour cycle, which regulate a number of body processes such as the sleep/wake cycle and changes in the core body temperature
Biological rhythms definition
distinct patterns of changes in body activity that conform to cyclical time periods. Biological rhythms are influenced by internal body clocks (endogenous pacemakers) as well as external changes to the environment (exogenous zeitgebers)
chronotherapeutics
how medical treatment can be administered in a way that corresponds with biological rhythms
Siffre
- spends multiple periods of extended time underground to measure the effects on his biological rhythms.
- After having no natural light or sound after one exhibition he resurfaced in mid-September believing it to be mid-august in the Southern Alps.
- The biological rhythm settled to 25 hours (normal is 24) and he continued to fall asleep and wake up on a regular schedule.
Aschoff and Wever
- Convinced participants to spend 4 weeks in a WW2 bunker with no natural light
- Most participants displayed regular 24-25 hour circadian rhythms
- One participant experienced a sleep/wake cycle of 29 hours
similarities between Siffre and Aschoff’s research
Both studies show that the ‘natural’ sleep/wake cycle may be just over 24 hours but it is entertained by exogenous zeitgebers associated with our 24 hour clock eg typical meal times
Folkard et al displays evidence to show that we should not overestimate the influence of exogenous zeitgebers:
- Studied 12 people living in a dark cave for 3 weeks, retiring to bed when the clock said 11.45 and waking up at 7.45
- Gradually, researchers sped up the clock but did not tell the participants so the day was eventually only 22 hours
- Only 1 participant could comfortable adjust to the new regime
- This suggests the existence of a strong free-running circadian rhythm that cant be overridden by exogenous zeitgebers
Boivin et al
found that night workers engaged in shift work experience a period of lack of concentration at about 6 in the morning, so mistakes more likely
Boten et al
found the timing of taking aspirin (reducing blood platelet activity) important as heart attacks normally occur in the morning
Knutsson
found that shift workers are 3 times more likely to develop heart disease that people working normal work patterns
Solomon
found that high divorce rates in shift workers may be due to strain of deprived sleep and influences like missing out on family events
Czeisler et al
ound individual differences varying from 13-65 hours
Duffy et al
found some people like to go to bed early and wake up early (larks) but some do the opposite (owls)
Wolfson and Carskadon
recommended that school should start a couple hours later to fit teenagers chronotype (sleep pattern). But shifting the day is disruptful to teachers and parents. It also limits the number of available after school activities
I
Shift work
strength
Research provides understanding of the consequences that occur when circadian rhythms are disrupted (desynchronisation)