circ system Flashcards

1
Q

blood

A

)ONLY FLUID TISSUE IN BODY
-this enables it to circulate through heart, arteries, capillaries and veins.
-takes nourishment and O2 to cells takes away waste
-

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2
Q

plasma

A
  • contains ions and proteins

- 90% water

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3
Q

plasma protein- Albumin

A

transports, maintains osmotic pressure

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4
Q

plasma protein-Globulin

A

antibodies-protects against foreign things

-transport

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5
Q

Fibrinogen

A

clotting- becomes visible during clotting

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6
Q

function of blood

A

regulates- temp, pH, fluid volume
transport-gases, nutrients, waste
protection- against blood loss and protection

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7
Q

RBC- Erythocytes

A

Are biconcave shaped cells, that carry O2 and CO2, only live 120 days, they determine blood trpe.

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8
Q

RBC shape

A

Biconcave due to loss of nucleus before entering bloodstream, shape gives maximum surface area for gas exchange, plus maximum flexibility for navigating through small spaces.

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9
Q

Inside cell membrane of RBC

A

red pigment called hemoglobin- 4 heme group, blood is bright red whn carrying oxygen -4 globin groups- protein part, darker blood and 4 iron molecules which carry the oxygen- rbc can have 1 bilion oxygen molecules.

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10
Q

erythrocyte production

A

1-born in born in red bone marrow
2-kidney releases erythropoiten-stimulis for bone marrow (homeostatic)
3-120 days cells loose flexibility, get stuck on liver or spleen and die
4-haemaglobin is split into heme and globin
5-heme is made into iron and resused and stored or a pigment called biliruben and excreted in faeces
6-globin is broken down and reused

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11
Q

Never let monkeys eat bananas

A
neutrophils
lymphocytes
monocytes
Eosinophils
basophils
In order of what there is the most of in wbc
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12
Q

Leukocytes

A

defend against disease, leave and return to the bloodstream, less than 1% of blood volume- every 1000 Rbc to 1 wbc

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13
Q

Neutrophils

A
  • polymorphic microphages- engulf bacteria then die
  • 1st to arrive to site of acute infection
  • 60-70% commmon
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14
Q

lymphocytes

A

B cells produce antibodies

T cells protect against viral infection cells- cancer

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15
Q

monocytes

A

largest, leaves vessel to become microphage-engulfs bacteria to survive

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16
Q

Eosinphils

A
  • destroys worms
  • destroys antigen complexes
  • lessens severity of inflammation
17
Q

basophils

A

rare
stimulates inflammation by releasing histamine
secretes herapin- anticoagulent

18
Q

platelets

A
  • fragments of large cells

- aid clotting by forming temporary plug before the clot can form

19
Q

systematic circulation

A

blood moves from heart to all cells and tissues and then back to the heart

20
Q

pulmonary circulation

A

carries blood from the heart to the lungs and back to the heart

21
Q

lymphatic circulation

A

every single tissue in the body has fluid in it, this fluid constantly is removed ans replaced by lymphatic circulation

22
Q

walls of arteries and veins

A

tunic intima- innermost layer- endothelium
tunic media- middle layer-smooth muscle
tunic externa- outermost -connective tissue

23
Q

veins

A

-carry blood to the heart, systematic veins carry de-oxygenated blood.
they are reservoirs, that have low blood pressure - so valves are required which are the folds of the tunica intima, these valves ensure no backflow of blood.

24
Q

venules

A

blood drains from capillaries into venules, which then empty into veins

25
Q

capillaries

A
  • destination of transport substances due to holes in there thin endothelial membrane layer, exchange of substances occur here between tissue and blood.
  • capillaries occur in beds (like spiderwebs) for parallel flow. these beds are either bypassed or not, depending on amount of pressure needed.
26
Q

Arterioles

A

smallest arteries, carry blood into capillaries. Regulate flow into capillary.

  • diameter gets smaller (vasoconstriction) because drag of blood against wall increases.
  • diameter gets larger (vasodilatation) increased flow into working tissue
27
Q

lumen

A

is the space through which blood flows lumen diameter is altered by constriction and dilation

28
Q

vessels

A

have same 3 tunics as veins, have thinner walls with more internal veins.
-collecting vessels in the skin travel with superficial veins
-deep vessels travel with arteries
function- collect lymph from lymph nodes, carry lymph to and away from lymph nodes

29
Q

lymphatic capillary structure

A

-begin as blind ended tubes
-easily opened flap like mini valves
-located throughout the body except in bone marrow, bone, teeth and nervous system
FUNCTION
return excess fluid and leaked protein to blood
carry absorbed fat from intestine to blood

30
Q

how lymphatic capillaries are formed

A

-at capillary beds fluid is forced out of blood
- most is reabsorbed
some fluid is left in space between tissues and vascular cappilaries (3L/day of IF (intersitial fluid))
-this fluid plus leaked plasma protein enters lymph capillary
- this is now a lymph capillary and is returned to blood

31
Q

lymph node structure

A

vary in size and shape, most are bean shaped. they have more afferent vessels entering them than efferent ones leaving at the hilus. they have 2 regions medulla (central core contains phagotic microphages) and cortex (outer part of node, covered by fibrous capsule, has collection of lymphocytes B and T cells).

32
Q

Function of lymph node

A

filters lymph before it returns to blood, slows flow through lymph node to allow antigen removal and protection. Defense cells such as macrophages (engulf and destroy foreign substances (antigens)) and lymphocytes (B and T) provide immune response to antigens) are located within node.

33
Q

inflamatory response

A

second line of defense to damaged skin, 4 signs Heat, Pain, Swelling, Redness, inflammation leads to a chain of events leading to protection and healing.