Ciclo de Krebs Flashcards

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1
Q

La citratocintasa une y forma

A

Une al acetil CoA y Oxalacetato, formando citrato
Se libera la coenzima A por hidrolisis

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2
Q

Enzima que hidrata y deshidrata
Pasando de citrato a isocitrato

A

Aconitasa

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3
Q

La isocitrato deshidrogenasa crea un NADH+H para formar

A

De Isocitrato a alpha cetoglutarato

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4
Q

Para formar Succinil CoA se necesita
Liberando _____ e ingresando ____

A

Pasar el alpha cetoglutarato a succinil CoA, por la enzima alpha - cetoglutarato deshidrogenasa

Co2 —- SHCoA

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5
Q

Que ocurre en la reaccion 5

A

La succinil sintetasa libera un GTP y a la SHCoA
Formando Succinato

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6
Q

Enzima que pasa de succinato a fumarato

A

Succinato deshidrogenasa formando un FADH+H

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7
Q

La fumarasa forma

A

Malato a partir del fumarato

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8
Q

Enzima que forma oxalacetato

A

Malato deshidrogenasa

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9
Q

Las enzimas deshidrogenasas liberan

A

NADH y FADH

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10
Q

ATP totales de un ciclo de krebs (1 acetil CoA)

A

12

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10
Q

Donde ocurre el ciclo de Krebs

A

En la matriz mitocondrial

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11
Q

Cuales son las 3 subunidades cataliticas de la piruvato deshidrogenasa

A

E1 - Piruvato deshidrogenasa
E2 - Dihidrolipoil transacetilasa
E3 - Dihidrolipoil deshidrogenasa

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12
Q

Acetil-CoA y NADH Inhiben a

A

Alostericamente a la Piruvato deshidrogenasa

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13
Q

Que activa a la Piruvato deshidrogenasa

A

Piruvato, ADP y la insulina

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