CI Flashcards
(100 cards)
What are the three phases of healing?
inflammation, proliferation, maturation/remodeling
What is the hallmark of the inflammatory phase of healing?
controlling bleeding and fighting infection
What are the cardinal signs of inflammation?
pain, redness, warmth, edema, decreased function
Key cells in the inflammatory phase
PMN, platelets, macrophages, mast cells
What are the 3 keys of the proliferative phase?
angiogenesis, granulation tissue, wound contraction
What are the key cells of the proliferation phase?
angioblasts, fibroblasts, myofibroblasts, keratinocytes
How does tissue change in the remodeling phase?
Type 1 Collagen to Type 3 Collagen
When does greatest tissue change in the remodeling phase?
First 6-12 months
What are permanent tissue changes from a wound?
decreased sensation, 80% strength, loss of sweating ability
What is the best temperature for wound healing?
37-38 deg C
What co-morbidities can affect wound healing?
PVD, anemia, COPD, cardiac, HIV/AIDS, diabetes
What medications can delay healing
steroids, chemotherapy, NSAIDS
What behavioral factors decrease wound healing?
EtOH, smoking
T/F - it is good to use antiseptics for a prolonged time
F
What is primary intention?
Closure w/ stitches/staples
What is secondary intention?
Closure of the wound by itself
What is delayed primary intention?
Wait for a period of time, then close w/ stitches
What does DIME stand for?
Debridement, inflammation/infection control, moisture balance, edge effect
Name: viable tissue, 2 types of necrotic tissue
granulation tissue, slough, eschar
Sinus tract
a wound entrance w/ no exit
What is a wound tunnel
entrance + exit
fancy names for rolled or callused wound edges
epibole, hyperkeratosis
What does maceration mean
skin pruning - too much moisture
What are hallmarks of a chronic wound?
Low mitotic activity, increased inflammatory cytokines, high levels of proteases, persistence in time