Chronic Stable Angina

Question 1

Atherolsclerotic narrowing of one or more major coronary arteries. Includes angina pectoris, unstable angina, acute myocardial

Answer 1

coronary heart disease (CHD)

coronary artery disease (CAD)

Question 2

imbalance between myocardial oxygen supply and demand resulting from atherosclerotic CAD

Answer 2

ischemic heart disease (IHD)

Question 3

clinical syndrome of myocardial ischemia characterized by a deep, poorly localized chest or arm discomfort associated withy physical exertion or emotional stress and releved promptly by rest or nitroglycerin

Answer 3

angina pectoris

Question 4

constellation of clincal symptoms that are compatible with acute myocardial ischemia

Answer 4

acute coronary syndrome

Question 5

ST-segment elevation requiring immediate reperfusion therapy (NSTEMI)

Answer 5

Acute myocardial infarction (MI). May be referred to as Q-wave MI

Question 6

Ischemia is severe enough to cause sufficient myocardial damage and the release of markers of myocardial injury

Answer 6

Non-ST-segment elevation MI (NSTEMI). May be referred to as non-Q-wave MI

Question 7

no biochemical markers of myocardial necrosis are released

Answer 7

unstable angina

Question 8

clincal syndrome of rest paint and reversible ST-segment elevation without enzyme elevation indicating AMI, usually due to coronary vasospasm

Answer 8

variant angina

Question 9

percutanous placement of catheter in the femoral artery and advancement through the vasculature to the tip of the coronary arteries; radiocontrast dye is injected to determine the location and extent of atherosclerosis

Answer 9

coronary angiography

Question 10

also known as angioplasty, a balloon catheter is placed during angiography and is inflated to re-open the diseased vessel; an intracoronary stent can then be placed to maintain patency of the vessel

Answer 10

percutaneous coronary intervention

Question 11

myocardial oxygen demand (MVO2) is determind by _________

Answer 11

work load

Question 12

What are the determinants of myocardial oxygen demand?

Answer 12

heart rate, contractiliy, intramyocardial wall tension during systole

Question 13

Oxygen supply is determined by _______________

Answer 13

coronary blood flow and oxygen extraction

Question 14

What is normal oxygen extraction?

Answer 14

70-75%

Question 15

When does oxygen extraction plateau?

Answer 15

80%