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FC - Haematology > Chronic Lymphocytic Leukaemia > Flashcards

Chronic Lymphocytic Leukaemia Flashcards

1
Q

True or false, CLL is the most common Leukaemia in the Western World?

A

True

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2
Q

Median age of presentation of CLL?

A

70s

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3
Q

Complications of CLL

A

Richter transformation (leukaemia cells enter lymph node) –> Non-Hodgkin’s lymphoma (high grade)

Hypogammaglobulinemia
Warm autoimmune haemolytic anaemia

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4
Q

Pathognomic cell type seen on blood film?

A

Smear/Smudge cells

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5
Q

Give 3 poor prognostic factors for CLL

A

Late age at presentation
Lymphocyte count > 50
CD38 expression positive
p53 mutation
Deletion of 13q part of chromosome

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FC - Haematology (5 decks)

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