Chronic Disease Management Flashcards

1
Q
  1. INR and warfarin
A

International normalised ratio –
- Normal INR is 1, those on warfarin should aim for 2–3 (2.5 as an ideal).
- People with an INR higher than the normal range who are not taking warfarin may have a medical condition.

Warfarin –
- Vitamin K antagonist (blocks vitamin K epoxide reductase) leading to decrease in factors 2, 7, 9 and 10.
- Regular blood tests, take at same time every day, do not double dose to catch up.

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2
Q

History taking for INR and warfarin

A

Intro –
- I understand you are… and I can see from your results that your INR is…
- Check patients understanding of INR and warfarin;
= Warfarin is an anticoagulant and that means its job is to stop the blood from clotting too easily.
- Explain what INR is and the risks of it being high/low;
= Provides information about someone’s bloods tendency to clot.
= The higher the INR, the longer it takes the blood to clot and so the increased bleeding risk. The lower the INR, the thicker the blood so increased clotting risk.
- Explain why they are on warfarin.
= Commonly used to treat blood clots (DVT/PE/prevent stroke in AF).

Compliance = needs to be taken every day at the same time and you should not double dose

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3
Q

INR and Warfarin: Presenting complaint of Px

A

Ask how they are feeling?
- Any recent infections/illnesses?
- Any diarrhoea/vomiting?
= Bloody/dark stool or vomit.

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4
Q

High INR symptoms

A
  • Any high INR symptoms?
    = Headache, severe stomach ache.
    = Increased bruising.
    = Prolonged bleeding after minor cuts/menstrual bleeding/gum bleeding.
    = Blood in urine.
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5
Q

Low INR symptoms

A
  • Any low INR symptoms?
    = Sudden weakness/numbness/tingling in any limb, visual changes, inability to speak (stroke symptoms).
    = New pain, swelling, redness, heat in body parts or new SOB or chest pain (DVT/PE symptoms).
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6
Q

INR and warfarin: Patient medical history

A

Liver failure (lack of clotting factors).
- Bleeding disorders (haemophilia, factor 7 deficiency)

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7
Q

INR and warfarin: Drug history

A
  • Do you know how many times you are meant to be taking the warfarin?
  • How and when do you take it? Have you missed any doses? If so, did you double dose?
    = Taking too much anticoagulant medication can cause increased INR.
  • Are you finding this okay or are you struggling to keep up with the dose – if so, why?
  • Any other medications;
    = Aspirin, NSAIDs, herbal medication (St John’s wart), OCP/HRT, omeprazole, prednisolone, rifampicin
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8
Q

Social History

A
  • Any diet changes?
    Foods containing vitamin K are green fruit/veg like broccoli, kale, celery, cucumber, green beans, green apples/grapes, pears, avocado
    Not necessary to cut out these veg but keep consistent if on Warfarin
    Binge drinking alcohol can INCREASE INR
    Smoking can INCREASE INR
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9
Q

INR Warfarin advice

A

Decreasing the risk of bleeding:
- Avoid activities that cause bleeding or bruising
- Brush/shave gently
- Tell dentist and any other HCP that you take anticoags

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10
Q

Treating elevated INR

A
  • Vitamin K
  • Blood components may be given during a transfusion to help stop bleeding
  • If there’s no clear reason then warfarin dose can be decreased and INR rechecked
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11
Q

Treating low INR

A

LMWH, warfarin
Compression stockings if immobile

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12
Q
  1. HbA1c
A

Normal = 42 mmol/L or <6.0%
Pre-diabetes = 42 - 47 mmol/L or 6 - 6.4%
Diabetes > 48 mmol/L or 6.5%

Benefits of lowering Hba1c:
- reduces risk of: retinopathy, neuropathy, diabetic nephropathy
- less likely to suffer from: cataracts, heart failure, amputation

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13
Q

History for HbA1c

A

I understand you are… and I can see from your results that your HbA1c is…
- Check when the patient was diagnosed, if it’s T1/T2 and their understanding of their diabetes and HbA1c;
= HbA1c shows us the average blood glucose level over the previous 2–3
months as the sugar sticks to cells in our blood.
- How well do you think your diabetes is being managed?
- Explain benefits of lowering HbA1c;
= Reduces the risk of retinopathy (eye problems), neuropathy (losing
sensation in your feet/hands) and diabetic nephropathy (kidney issues).
= Less likely to suffer from cataracts, heart failure and amputation.

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14
Q

Presenting complaint of HbA1c

A

How are you feeling?
Any recent infections/illnesses?
= D+V/illnesses can affect the amount of insulin required
Any hospital admissions for DKA/hypos?
Any symptoms of diabetes?
- Polyuria, polydipsia, weight loss, vision changes, tingling in feet, impotence (ED)

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15
Q

Past medical history of HbA1c

A

Any CVD/cerebrovascular/renal/visual complications
Any co-morbidities
HbA1c can be falsely raised in:
- Kidney disease
- Chronic excessive alcohol intake
- Vitamin B12 def
HbA1c can be falsely decreased in:
- Acute/Chronic blood loss
- Sickle cell disease
- Thalassaemia

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16
Q

Drug history of HbA1c

A

What diabetic medications do you take?
How/when are you taking the medication?
Any side effects?
Are you finding it okay or are you struggling to keep up with the dose? If so - why
Injecting correctly (site rotation), monitoring glucose levels?
Any other medications/changes?

17
Q

Social History

A

Activities of Daily living:
- How is your mood/sleep?
- Are home circumstances okay?
- Do you feel like your disease is affecting your ADLs
Diet:
- Adhering to dietary restrictions
- Been on a recent diet/tried to lose weight?
- Exercise
- Smoking + alcohol

18
Q

Advice for lowering HbA1c

A

Dietary modifications;
- Awareness of snacking and sugary foods/carbs affecting the blood sugar
level.
- Physical activity;
- Regular exercise can help stop blood sugar levels rising.
- Check with doctor first because some diabetes medicines can lead to hypoglycaemia if you exercise too much.

Take extra care when ill;
- “Sick day rules” check blood sugar more regularly (4h), keep taking diabetes medications even if you don’t feel like eating, contact diabetes team, check ketones.

Monitor blood sugar level –
- So you can spot an increase early and take steps to prevent it.
- Support available;
- GP, diabetes nurses, online resources, training courses.

19
Q
  1. Peak flow/spirometry
A

Peak flow
- Take your peak flow before using the preventer inhaler
- Always use the same peak flow meter

Spirometry
- Measures functional lung volumes

Obstructive lung disease
- Causes:
= Reversible (asthma) and irreversible (COPD)
= Bronchiectasis
= Inhaled foreign body, tumour
- Takes a long time to exhale (wheeze) so not much breathed out at 1 second but volumes not bad overall
= FEV1<FVC
= FEV1/FVC < 0.7 with FEV1<80% predicted

Restrictive lung disease
- Usually diseases of the interstitium affecting chest wall movement and elasticity;
= Scoliosis, kyphosis, ankylosing spondylitis.
= Neuromuscular diseases like Guillain-Barré syndrome, myasthenia gravis.
= Pulmonary fibrosis, sarcoidosis, asbestosis.
- Due to restriction, lung volumes are small and most of breath is out in the first:
second.
= FEV1/FVC > 80% because of the FVC being proportionally lower.

20
Q

History taking for Spirometry

A

I understand you are… and I can see from your results that your peak
flow/spirometry is…
- Check patients understanding of peak flow/spirometry and their condition –
= Peak flow test measures how fast you can breathe out so you can see how
well your lungs are working.
= Spirometry measures lung function, specifically the amount (volume) and
the speed (flow) of air that can be inhaled/exhaled.

21
Q

Presenting complaint

A
  • How are they feeling?
  • Any recent illnesses/infections?
  • Any SOB?
  • Is there any particular time you notice your condition worsens (winter etc).
  • Enquire about red flags;
    = Wheeze is getting worse.
    = Affecting ADL.
    = Waking up at night with symptoms (SOB, cough).
    = Using reliever inhaler more than usual.
22
Q

Drug history

A
  • How well do you think your condition is being controlled?
  • What medications do you take? Which inhalers do you use and how often?
  • Do you take any other medications (if on steroids then severe).
  • Any beta-blockers.
  • Check inhaler technique and check inhaler use has been assessed by the nurse.
23
Q

Social History

A

Any (new) pets?
- Recent travel anywhere?
o Particularly to places that are polluted.
- Housing situation (damp)?
- Hayfever
- Smoking? Alcohol? Impact of condition on life.

24
Q

Exacerbations and Advice

A
  • Stop smoking.
  • Avoid precipitants.
  • Vaccination (flu).
  • Exercise.
  • Eating.
  • Support.

Exacerbations
Is there any particular time you notice that your asthma is worse e.g. is it worse during the winter months?
Any pets/any new pets?
Recent travel anywhere? (Your would want to be weary of places which are particularly polluted).
Housing - (there may be damp)?
Hayfever

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4. Inflammatory Markers (CRP/ESR)
CRP: - Non-specific marker. - Substance produced by the liver and increases in the presence of inflammation. - Acute marker. Routinely measured in assessment of disease activity of autoimmune/inflammatory conditions – - Rheumatology (RA, JIA, seronegative arthritis like ankylosing spondylitis, reactive arthritis and psoriatic arthritis), Crohn’s disease, Vasculitis, polyarteritis nodosa, Pancreatitis. Assistance with diagnosis and monitoring infection: - Infective endocarditis, Abscess post-op infection, Response to Abx. Differentiation between inflammatory conditions – - SLE vs. RA. - Crohn’s vs. UC. Causes for raised CRP – - Burns, trauma, Infections (pneumonia, TB), Chronic inflammatory diseases (SLE, vasculitis, RA), MI, IBD, cancers. ESR: - Increased fibrinogen means RBCs stick together and so fall faster. - Raised ESR = rate of fall quicker. - ESR rises and falls slowly. Causes for raised ESR – - Malignancy (Malignant lymphoma, Carcinomas of colon/breast), Haematological (Multiple myeloma, Anaemia of acute/chronic disease combined with iron deficiency anaemia), Connective tissue disorders (SLE, RA, Polymyalgia rheumatica and temporal arteritis), Infections (TB, acute hepatitis, bacterial).
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History taking for ESR/CRP
- I understand you are… and I can see from your results that your CRP/ESR is… - Check patients understanding of CRP/ESR and their condition = It’s a marker of inflammation which tells us that there could be a flare up in your condition or new infection detected.
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Presenting complaint
- How are they feeling? - Any recent illnesses/infections?
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Drug history
How well do you think your condition is being controlled What medication do you take? How often? Any issues taking your medication? Do you take any other medications?
29
Social history
Recent travel anywhere? Smoking? Alcohol? Impact of condition on life
30
Advice
Stop smoking Advice on disease management if they’re non-compliant
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5. LFTs
Albumin – - Low; = Can be a sign of malnutrition (Crohn’s/UC, coeliac). = Kidney disease, liver disease (hepatitis, cirrhosis). - High; = Severe infections/dehydration, chronic inflammatory diseases, hepatitis. Globulins – - Total proteins. Bilirubin – - High conjugated = liver/bile duct disease. - High unconjugated = Gilbert’s or haemolytic anaemia. Liver enzymes increase in – - Chronic high alcohol excess. - Obesity (especially in men). - Smoking (in women). - Drug reaction. ALP – - Bile duct obstruction stimulates ALP synthesis; = Increase in obstructive liver disease. = Non-hepatic origin like increased osteoblastic activity in Paget’s, osteomalacia, vitamin D deficiency. GGT – - Liver disease markers of drugs/alcohol (increases) AST or ALT – - Liver disease markers of drugs, toxins, viral (increases). GGT + ALP – - Biliary problems. AST + ALT – - Hepatic problems. GGT + ALP risen > AST + ALT – - Obstructive jaundice.
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History taking
I understand you are… and I can see from your results that your LFTs are… - Check patients understanding of LFTs and their condition – = Explain the relevant increased result.
33
Patient history
How are they feeling? Any recent illnesses/infections?
34
Patient medical history
Gallstones in the past Crohns/UC Surgery in past if malabsorption mat have had some bowel removed
35
Drug history
How well do you think your condition is being controlled? What mediation do you take? How often? Any issues taking your medication? Do you take any other medications.
36
Social history
- Recent travel anywhere? - Smoking? - Alcohol? - Recreational drugs/toxins? - Diet. - Impact of condition on life.
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Advice
- Stop smoking/alcohol/drugs. - Diet advice. - Advice on disease management if they’re non-compliant.