Chronic Dialysis Flashcards
Purpose of dialysis
remove toxins normally cleared by kidney and maintain euvolemia in patient
2 types of dialysis
hemodialysis = dialysis unit/home
peritoneal dialysis = home
Indications for starting dialysis
1) severe hyperkalemia
2) severe volume overload
3) uremic pericarditis
less severe symptoms = mild cognitive changes assoc with uremia would warrant dialysis if
patient has appropriate dialysis access (AV fistula or PD catheter)
if life threatening symptoms, dialysis must be weighed against
risk of catheter infection
is there a specific GFR for dialysis initiation
no specific GFR
no diff between early vs late start dialysis
forms of hemodialysis
hospital or dialysis center = 3x/week 3-4 hrs ea
home = 5-6x/week or nocturnal
Circuit of hemodialysis
1) blood removed by needle/catheter
2) enters tube with semi-permeable membrane
3) dialysate –> solutes move into dialysate (low concentration)
fluid removed by applying positive pressure to blood
4) blood returned
AVF
pros
cons
pros =
lowest infection rate
used longer than other types
cons =
take time to mature
AVG
pros
cons
pros =
synthetic grafts
used more quickly
higher primary success rate
cons =
fail quicker due to neointimal hyperplasia
higher infection risk
dual lumen catheter
pros
cons
pros
used immediately
cons
higher infection rate
where to place accesses?
NON DOMINANT ARM
IN STAGE 4
pros cons hemodialysis
pros = rapid removal of small MW solutes urea
precise control of ultrafiltration
Cons
fluid removal no physiologic
so must remove large volumes of fluid
not effective to remove large MW solutes/protein bound
complications of hemodialysis
1) infectious complications (gram positive = staph aureus and coag negative staph
2) hypotension, angina, or MI
3) disequlibrium syndrome
peritoneal dialysis mechanism
1) catheter into peritoneum
2) dialysate with high dextrose and high oncotic pressure into peritoneum
3) fluid and solute from blood to peritoneal cavity