Chromosomes and Meiosis Flashcards

1
Q

What are chromosomes?

A
  • long, thread-like structures
  • that form part of the chromatin network in the nuclei of cells
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2
Q

What are chromosomes made up of?

A
  • a strand of DNA wound around proteins called histones
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3
Q

How many chromosomes are in the somatic cells of diploid organisms?

A
  • the number of chromosomes in each cell is the same
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4
Q

What are the chromosomes of somatic cells made up of?

A
  • two sets
  • one chromosome of each pair comes from the mother and one comes from the father
  • therefore diploid cells
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5
Q

What is a homologous pair formed?

A
  • when a paternal chromosome and a maternal chromosome pair up
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6
Q

What does the DNA of each chromosome do?

A
  • replicated to form 2 identical threads or chromatids joined by a centromere
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7
Q

When does DNA replication occur?

A
  • in the interphase of a cell cycle
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8
Q

When do chromosomal threads become visible?

A
  • only when they shorten and thicken as a cell divides
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9
Q

What happens to the number of chromosomes in meiosis?

A
  • the number of chromosomes is reduced from two sets (2n) in the parent cell
  • to one set (n) in each of the daughter cells formed
  • i.e. the number of chromosome is halved
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10
Q

What is meiosis?

A
  • cell division that takes place in the reproductive organs of both plants and animals
  • to produce gametes in animals
  • and spores in plants
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11
Q

What are the characteristics of the gametes/spores formed in meiosis?

A
  • they are called haploid
  • as they only have one set of chromosomes
  • i.e. one chromosome from each homologous pair
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12
Q

Where does meiosis take place in animals?

A
  • the testes and ovaries
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13
Q

What is the formation of sperm cells in the testes called?

A
  • spermatogenesis
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14
Q

What is the formation of egg cells in the ovaries called?

A
  • oogenesis
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15
Q

Where does meiosis take place in plants?

A
  • in sporangia
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16
Q

What are microsporangia?

A
  • the pollen sacs in the male anthers
17
Q

What are megasporangia?

A
  • the ovules in the female ovaries
18
Q

What does abnormal meiosis result in?

A
  • chromosome abnormalities
19
Q

What is a way in which abnormal meiosis can occur?

A
  • chromosome non-disjunction
20
Q

When does chromosome non-disjunction occur?

A
  • when chromosomes fail to separate correctly during meiosis
21
Q

What happens if chromosome non-disjunction occurs in the sex chromosomes?

A
  • fertilisation involving one of these abnormal gametes will result in a zygote with either an extra or missing chromosome
  • a condition known as aneuploidy
22
Q

What is aneuploidy?

A
  • a condition wherein chromosomes fail to separate correctly during meiosis
  • resulting in a zygote with either an extra or a missing chromosome
23
Q

What is a diagnosis?

A
  • the identification of the nature of an event
24
Q

What is a prognosis?

A
  • the prediction of how the event will develop
25
Q

What are some examples of aneuploidy?

A
  • klinefelter’s syndrome
  • down syndrome
26
Q

When does klinefelter’s syndrome occur?

A
  • when a boy is born with an extra copy of the x chromosome
  • when the sex chromosomes in the egg (or very rarely in the sperm) split unevenly
27
Q

What are some of the possible symptoms of klinefelter’s syndrome?

A
  • sparse body hair
  • enlarged breasts
  • small testicles and penis
  • not very deep voices
  • infertility
28
Q

When does down syndrome occur?

A
  • when children are born with an extra copy of chromosome number 21
29
Q

How does down syndrome come about?

A
  • during oogenesis, the 2 number 21 chromosomes do not separate properly during anaphase 1
  • both go into 1 daughter cell instead of 1 into each of the 2 cells formed
30
Q

What are some down syndrome characteristics?

A
  • varying degrees of mental retardation
  • distinctive flattened facial features with slanting eyes
  • often heart defects
31
Q

What is a karyotype?

A
  • a set of chromosomes in a cell
32
Q

What do karyotypes show?

A
  • the number, size and shape of the chromosomes during metaphase of mitosis
33
Q

What are non-sex chromosomes called?

A
  • autosomes
34
Q

What are sex chromosomes called?

A
  • gonosomes
35
Q

Why are karyotypes useful?

A
  • can show whether a cell comes from a male or a female
  • can show abnormal chromosomes